Previous Article in event
Next Article in event
Reactions of Acetoacetates With Electron-deficient Anilines
Published: 30 November 2007 by MDPI in The 11th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis
Abstract: The reaction of anilines, having electron-withdrawing substituents such as chloro- or trifluoromethyl groups, with acetoacetates was studied. Using the "watering protocol" , mainly acetanilides were obtained which were intended ty cyclize to 2-quinolones. However, in contrast to electron-rich anilides, it was not possible to obtain cyclized products from electron-deficient anilides.