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Reactions of Acetoacetates With Electron-deficient Anilines
Published:
30 November 2007
by MDPI
in The 11th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract: The reaction of anilines, having electron-withdrawing substituents such as chloro- or trifluoromethyl groups, with acetoacetates was studied. Using the "watering protocol" [5], mainly acetanilides were obtained which were intended ty cyclize to 2-quinolones. However, in contrast to electron-rich anilides, it was not possible to obtain cyclized products from electron-deficient anilides.
Keywords: n/a
