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Reactions of Acetoacetates With Electron-deficient Anilines
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1  Institut für Chemie, Organic Synthesis Group, Karl-Franzens-University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria

Abstract: The reaction of anilines, having electron-withdrawing substituents such as chloro- or trifluoromethyl groups, with acetoacetates was studied. Using the "watering protocol" [5], mainly acetanilides were obtained which were intended ty cyclize to 2-quinolones. However, in contrast to electron-rich anilides, it was not possible to obtain cyclized products from electron-deficient anilides.
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