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Periodic Classification of Human Immunodeficiency Virus Inhibitors
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1  Institut Universitari de Ciència Molecular, Universitat de València, Edifici d'Instituts de Paterna, P. O. Box 22085, E-46071 València, Spain

Abstract: Classification algorithms are proposed based on information entropy and applied to 13 human immunodeficiency virus type 1 inhibitors. A number of results are compatible with the data suffering combinatorial explosion. After the equipartition conjecture, entropy production is most uniformly distributed. In ddI the formula is N4O3S0P0 , X = F, Cl; it is selected as a reference . In most cases (ddI, ddC, d4T, novel proposed ligand) the formula is N3–4O3S0P0X0 , while in 3TC the formula is N3O3S1P0X0. The analysis compares well with other classification taken as good.
Keywords: n/a