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New Synthesis of 4,4'-Diethylaminoethoxyhexestrol dihydrochloride (Coralgil) and scaling up to multi-grams scale
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1  Institute of Applied Synthetic Chemistry, Vienna University of Technology, Austria

Abstract: We report here new preparation with significant yield improvement of title compound. For this purpose the preparation of 4,4'-diethylaminoethoxyhexestrol dihydrochloride under different reported and analogue conditions have been tried. The optimized synthesis of Coralgil is reported. The synthesis was also scaled up to multi-grams for chemo-genomics study.
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