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Study of a pH-sensitive Hologram for Biosensing Applications
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Academic Editor: VIJAYAKUMAR ANAND
Abstract:
Photopolymers are widely utilized as holographic recording media due to their ease of preparation and no wet chemistry post-processing. Holographic sensors constructed from pH-sensitive photopolymer film have several applications in biosensors and medical diagnostic field. However, the stability of photopolymer films in an aqueous medium is one of the important challenges in their application for biosensing. Furthermore, pH of the solution is another important parameter for biochemical reactions. In this work, we have compared the pH sensitivity and stability of our holographic grating against two widely utilized classes of buffers; Phosphate Buffered Saline (PBS) and Tris-Acetate-EDTA (TAE) at two different pH values of 7.36 and pH 8.0, respectively. It was observed that physiological pH (pH 7.36) had a negligible effect on the diffraction efficiency of the holographic sensor while it significantly deteriorated at a higher value of ~ pH 8.0. This high sensitivity towards the minute pH difference of our holographic sensor could potentially be exploited for pH-based biosensing applications such as urea detection.
Keywords: Holographic Sensors; Photopolymer Film; Biosensors, pH-Sensing
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26 March 2025
专业的essay代写 http://australiaway.org/a/essaydaixie/ 服务能够为学生提供高质量的学术文章，确保内容符合学术规范，同时帮助学生更好地理解课程要求。代写公司深知每个客户的独特需求，因此能够量身定制内容，确保最终的essay不仅符合教授的期待，还能展现学生的学术潜力。
