Sorghum is one of the most important food, fodder and technical crops grown in the world. Global climate change and environmental pollution with toxic industrial and agricultural waste are the most unfavorable environmental factors affecting the growth and development of sorghum, which leads to a decrease in product quality. The main purpose of this work is to study the effect of new plant growth regulators Methyur (derivative of sodium salt of 6-methyl-2-mercapto-4-hydroxypyrimidine), Kamethur (derivative of potassium salt of 6-methyl-2-mercapto-4-hydroxypyrimidine) and Ivin (N-oxide-2,6-dimethylpyridine) on the productivity of field-grown sorghum. Field experiments were carried out on grain sorghum (Sorghum bicolor L.) cv. Yarona, and sweet sorghum (Sorghum saccharatum L.) cv. Favorite. Statistical analysis showed that the productivity parameters of 4 month-old sorghum plants obtained from seeds treated before sowing in the soil with water solution of Methyur, Kamethur or Ivin at a concentration of 10^-7M, increased as follows: the average panicle length (in cm) increased by 7% - 20% - for grain sorghum cv. Yarona and by 25% - 37% - for sweet sorghum cv. Favorite, accordingly, and the average fresh weight of grain (in gram) increased by 13% – 26% - for grain sorghum cv. Yarona, and by 24% - 38% - for sweet sorghum cv. Favorite, compared to control. Based on the results obtained, it is proposed to use new plant growth regulators Methyur, Kamethur and Ivin to increase the productivity of sorghum crops.