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Synthesis of a hybrid molecule based on biologically active 5Z,9Z-eicosadienoic acid and vanillin
* 1 , 1 , 2 , 2
1  Institute of Petrochemistry and Catalysis, Russian Academy of Sciences
2  N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Academic Editor: Julio A. Seijas


A hybrid compound based on (5Z,9Z)-eicosa-5,9-dienoic acid and vanillin was synthesized in high yield (94%) using a new intermolecular cross-cyclomagnesiation reaction of aliphatic and O-containing 1,2-dienes catalyzed by Cp2TiCl2

Keywords: 1,2-dienes; cross-cyclomagnesiation; 1,2-dienes; cross-cyclomagnesiation; vanillin