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Microwave Enhanced Knoevenagel Reaction: an expeditious method to prepare 3-benzylidene-1,3-dihydroindol-2-ones
Published: 01 November 1999 by MDPI in The 3rd International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis
Abstract: Knoevenagel reaction has been object of a complete study1, recently the enhancement of this reaction by microwave heating has been reported by several groups2. We became interested in 3-benzylidene-1,3-dihydroindol-2-ones, as they have been reported as natural products from Isatis indigotica3, although they have been known as pharmacological agents from several years4.