Nitrothiophenes as Electrophiles in Polar Diels-Alder reactions. Solvent Effect and Microwave Irradiation

Claudia D. Della Rosa; Pedro Mancini

doi:10.3390/ecsoc-17-c004

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Nitrothiophenes as Electrophiles in Polar Diels-Alder reactions. Solvent Effect and Microwave Irradiation

Claudia D. Della Rosa

¹,

Pedro M.E. Mancini

^{*

2}

¹ Área Química Orgánica- Departamento de Química- Facultad de Ingeniería Química, Universidad Nacional del Litoral. Santiago del Estero 2829. (3000) Santa Fe, Argentina. FAX: +54-342-4571162. *e-mail:pmancini@fiq.unl.edu.ar
² Laboratorio Fester–IQAL (UNL-CONICET)– Facultad de Ingeniería Química – Santiago del Estero 2829, (3000), Santa Fe, Argentina.

Published: 31 October 2013 by MDPI in The 17th International Electronic Conference on Synthetic Organic Chemistry session Microwave Assisted Synthesis

https://doi.org/10.3390/ecsoc-17-c004

Abstract: In this work the electrophilic behaviour of nitrothiophenes in polar Diels-Alder toward dienes of different nucleophilicity is studied. In thermal conditions the reactions were development in molecular solvents and in protic ionic liquids trying to compare the solvent effects on this class of reactions. In the presence of these solvents the reaction system was exposed to microwave irradiation as a complement of reaction conditions.

Keywords: nitrothiophenes, Diels-Alder, microwave

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Claudia D. Della Rosa

Pedro Mancini