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Versatility of Silsesquioxane-Based Materials for Antimicrobial Coatings
1 , 2 , 2 , * 2
1  "Costin D. Nenitescu" Centre of Organic Chemistry, 202B Splaiul Independentei, 7114 Bucharest, Romania
2  Petru Poni Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania

Abstract: This paper is dealing with the state of the art of antibacterial nanostructured coatings with silsesquioxane content along the last decade. As follows, the requirements for achieving efficient coatings, chemical functionalization methods, working mechanisms and a classification of different silsesquioxane-based materials will be provided in order to have a complete overview of their most recent breakthrough for antibacterial/antifungal applications.
Keywords: antimicrobial, silsesquioxane, nanocomposite
Comments on this paper
Marinella Sandros
What are the techniques available to compare the effectiveness of the proposed antimicrobial materials?
Nedal Abu-Thabit
May be one can prepare discs and use Kirby bauer test‬‏. This will provide a quick prediction of various formulations.

Nedal Abu-Thabit
Also, one may try to place the coated parts in contaminated solution and stir it for long time (12 hours to 1 day) at room temperature. If the bacerial count decreased gradually in a reasonable trend, this means that the contact between the coating and the pathogens was effective for inactivation. Although this is NOT exactly what is happenning in dry conditions, but this can memic conditions for applications under immersed conditions such as ships and submarines.

Mihaela  Olaru
In-vitro antimicrobial susceptibility testing can be performed using a variety of techniques, the most common ones being agar dilution, disk diffusion, broth micro- and macrodilution, and concentration gradient tests. Each of these above-mentioned procedures requires the use of specific testing methods and conditions, and the identification of appropriate quality control organisms along with their specific quality control ranges. In order to increase the accuracy and rapidity of antimicrobial susceptibility testing, the use of genotypic procedures and microarray for the detection of antimicrobial resistance genes have been alos applied during last year's.

Nedal Abu-Thabit
antimicrobial action of silver nanoparticles
ALSO, catalytic action of silver nanoparticles can promote the generation of reactive oxygen species (ROS) and lead to the damage of DNA by exerting oxidative stress

Nedal Abu-Thabit
antimicrobial action of quaternary amine salt
this very good reviews for antimicrobial polymers that can be embedded in POSS: