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Comparison of Minimal Inhibitory Concentration of Porphyrin Compounds Against Bacillus Subtilis Under Irradiation With Visible Light
Published: 03 November 2014 by MDPI in The 18th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural Products Chemistry
Abstract: In this study, the effect of meso-tetrakis (N-methyl-3-pyridyl)porphyrin (TMPyP(3)), meso-tetrakis (4-N, N, N-trimethylanilinium) porphyrin (TAPP) and their zinc compounds irradiated with visible light, on a Gram positive bacterium, Bacillus subtilis, was investigated and compared. MIC, MBC and inhibition zones produced by these compounds were determined and the bacteria numbers were counted. The results indicate that TAPP and its zinc compound have more effective inhibitory activity than others against this bacterium.
Keywords: Bacillus subtilis; photo-inactivation; Tetra-cationic porphyrin; minimal inhibitory concentration