Background/Objectives: Dementia represents a complex syndrome in which biological, psychological, social, and cultural processes converge. Although its clinical features are well documented, less attention has been given to the lived experiences of patients and caregivers and their role in shaping illness trajectories. This study aimed to investigate risk factors, behavioral manifestations, and quality of life in dementia from an anthropological perspective, focusing on the interaction between comorbidity, cognition, lifestyle, cultural beliefs, and caregiving contexts.
Methods: A cross-sectional, observational study was carried out with family caregivers of individuals diagnosed with dementia who accessed specialized neurological and psychiatric care in Bucharest, Romania. Caregivers completed an anthropological questionnaire capturing socio-demographic data, comorbid conditions, lifestyle behaviors, relational dynamics, and cultural perspectives. Descriptive and inferential analyses examined associations between clinical, social, and cultural variables.
Results: Patients were predominantly older women living with multiple chronic conditions, most frequently neurological and cardiovascular. Cognitive impairment was more severe among individuals with lower levels of education and limited financial resources. Disturbances in appetite and sleep were common and frequently associated with diminished physical activity and reduced wellbeing. Disclosure of diagnosis elicited diverse emotional responses, with families describing processes of adaptation as ambivalent, nonlinear, and often marked by anxiety or sadness. Cultural beliefs and spirituality played a central role in shaping explanatory models and coping strategies, with reliance on religious practices, alternative therapies, and traditional interpretations frequently reported.
Conclusions: These findings suggest that dementia in this context is not solely a product of biological decline but is deeply embedded in socio-economic conditions and cultural frameworks. Addressing these intersecting influences through integrative, culturally responsive models of care may improve outcomes for both patients and caregivers.
