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NaBH4, CH3CO2H, Pd/C as a Reagent System to Hydrogenate Activated Alkenes Without O-or N-Debenzylation
Published:
30 October 2015
by MDPI
in The 19th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract: NaBH4, CH3CO2H, Pd/C has been described as a reagent system to hydrogenate alkenoates and alkenones. Here, we show that O-debenzylation does not occur under the conditions, making it possible to hydrogenate a double bond under Pd/C catalysis without O-debenzylation or N-debenzylation.