Urban resilience requires the integration of ecological, social, and functional capacities. However, existing approaches in urban design favor specialized methodologies that are, at the same time, often characterized by a sectoral and siloed approach, lacking diagnostic tools that capture cross-dimensional interdependencies across spatial scales. This study develops a Creative Diversity framework that unifies these dimensions into a coherent analytical structure for diagnosing resilience deficits in adaptive urban transformation processes. Creative Diversity is articulated through three conceptual dimensions: Space for Nature, addressing ecological connectivity and environmental performance; Space for Community, addressing social inclusivity and cultural identity; and Space for Function, addressing functional flexibility and economic viability. The framework intersects these dimensions with two fundamental resilience capacities: adaptive capacity to absorb disturbances and transformative capacity to reorganize toward new pathways. This intersection forms a diagnostic matrix that systematically identifies resilience deficits across scales. The framework was validated through a case study of Villa Guzzi and its surrounding neighborhood in Lecco, Italy, using multi-scale spatial evidence including geospatial analysis, municipal planning data, and on-site survey. The assessment revealed that resilience deficits across the six dimensions are structurally interconnected, with weaknesses in one dimension reinforcing deficits in others. Cultural identity was the only dimension to reach the acceptable baseline, yet this isolated strength did not generate systemic resilience. This pattern was consistent across both neighborhood and site scales, confirming that multi-scale and cross-dimensional diagnosis is essential for understanding the compounding nature of urban vulnerability. These findings demonstrate that effective urban resilience assessment requires diagnostic tools capable of integrating ecological, social, and functional dimensions within a unified structure. The Creative Diversity framework provides such a methodology, contributing to integrated approaches for adaptive urban transformation.