Please login first
One-pot three-component Mannich-type reaction catalyzed by functionalized ionic liquid
1 , * 2 , 2
1  Chemistry & Chemical Engineering Research Center of Iran, Tehran 14968-13151, IRAN
2  Research Laboratory of Green Organic Synthesis, Department of Chemistry, Iran University of Science and Technology, Tehran 16846, Iran

Abstract: Several ionic liquids used as catalyst for three-component Mannich reactions of aldehydes, amines, and naphthols at room temperature. The used ionic liquids include 1-butyl-3-methylimidazolium tetrafluoroborate ([Bmim]BF4), 1-octyl-3- methylimidazolium tetrafluoro-borate ([Omim]BF4), 1-ethyl-3-methylimidazolium tetrafluoroborate ([Emim]BF4), butyl dimethylimidazolium tetrafluoroborate ([Bdmim]BF4), 1-octyl-3-methylimidazolium nitrate ([Omim]NO3), 1-methylimidazolium sulfuric acid ([Hmim]HSO4) and 1-methylimidazolium trifluoroacetic acid ([Hmim] Tfa). Higher yields were obtained in the presence of [Hmim]Tfa in comparison with other ionic liquids.
Keywords: One-pot, three-component, Mannich-type. ionic liquid