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The role of excipients in neglected tropical diseases
* 1 , * 2 , * 3
1  Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramon yCajal s/n, Madrid, 28040, Spain.
2  3Departamento de Farmacia, Facultad de Ciencias de la Salud, Universidad Cardenal Herrera-CEU, Moncada, Valencia, 46113, Spain.
3  School of Pharmacy and Biomedical Sciences, University of Portsmouth, St. Michael’s Building, White Swan Road, Portsmouth PO12DT, U.K.


Leishmaniasis is a neglected tropical disease responsible for the ninth largest disease burden in the world. Excipients are necessary for ensuring the stability and bioavailability of currently available antileishmaniasis drugs. In a recent work, we have evaluated the in vitro activity of 30 commercially available excipients against different Leishmania spp., their cytotoxicity and potential use for inclusion in novel formulations. Ref: Curr Top Med Chem. 2017 Jul 19.

Keywords: Excipients, leishmaniasis, amphiphile, surfactant, lipids, Eudragit, Labrasol, medium chain fatty acids, lauric acid, sodium deoxycholate