Substituted Quinolinones. Part 14. Synthesis of Novel Dispiro(heterocycle-n,2'-[1,3]dithietane-4',3"-quinolinedione) Derivatives Under PTC-conditions

Ahmed Khodairy; Mohamed Abass

doi:10.3390/ecsoc-14-00464

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Substituted Quinolinones. Part 14. Synthesis of Novel Dispiro(heterocycle-n,2'-[1,3]dithietane-4',3"-quinolinedione) Derivatives Under PTC-conditions

Ahmed Khodairy

¹,

Mohamed Abass

¹ Chemistry Department, Faculty of Science, Sohag University, Postal Code 82524, Sohag, Egypt
² Chemistry Department, Faculty of Education, Ain Shams University, Postal Code 11757, Cairo, Egypt

Published: 30 October 2010 by MDPI in The 14th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-14-00464

Abstract: The four-membered spiro-heterocycles; ethyl cyano(1-methyl-2,4-dioxospiro{1,3-quinoline-3,4'-[1,3]dithietane}-4'-ylidene)- acetate 2a, -malononitrile 2b, -acetylacetone 2c and thiazetidine isomer 3 were prepared under phase transfer catalysis conditions (PTC). The thermal treatment of dithietanes 2a–c led to the bis-quinolinyl sulfide 4. Some interesting nucleophilic addition followed by cyclization reactions were carried out with the dithietane 2a to give the corresponding novel dispiro derivatives 5–8, 10–13, and 15.

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Ahmed Khodairy

Mohamed Abass