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Investigation of the Appel reaction with bromotrichloromethane-triphenylphosphine (CBrCl3/PPh3)
1 , 1 , * 2
1  Department of Chemistry, UAE University
2  Department of Chemistry, United Arab Emirates University


The Appel reaction of an alcohol with CCl4/PPh3 and with CBr4/PPh3 produce alkyl chlorides and alkyl bromides, respectively. It was found that in the case of using CBrCl3-PPh3, a mixture of alkyl chlorides and alkyl bromides are formed. Dichloromethane (CH2Cl2) and acetonitrile (CH3CN) were used as solvents, where the reaction was found to be solvent-dependent. 

Keywords: Appel reaction, bromotrichloromethane, alkyl halide