A Triterpenoid Saponin from the Seeds of Ricinus communis

Ashutosh Srivastava; Chetna Dubey; Noor Khan

doi:10.3390/ecsoc-14-00478

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SYNTHESIS, CHARACTERIZATION and ANTIMICROBIAL PROPERTIES OF THIOSEMICARBAZONEDERIVED FROM α-CHLORALOSE

A Triterpenoid Saponin from the Seeds of Ricinus communis

Ashutosh Srivastava

Chetna Dubey

Noor Afshan Khan

¹ Department of Chemistry, Rani Durgawati University, Jabalpur, M.P. -482001 INDIA

Published: 31 October 2010 by MDPI in The 14th International Electronic Conference on Synthetic Organic Chemistry session Natural Products Chemistry

https://doi.org/10.3390/ecsoc-14-00478

Abstract: novel oleanen type triterpenoid, has been isolated from butanolic extract of the seeds of Ricinus communis. Its structure was elucidated as 3-O-[β -D-glucoronopyranosyl-(1→ 3)-α –L-rhamnopyranosyl-(1→ 2)β-D-glucopyranosyl]-4α,20α-hydroxy methyl olean-12-ene-28-oic acid on the basis of spectral evidences i.e. FTIR, ¹H NMR, ¹³C NMR and FAB-MS data. The isolated saponin was tested for its antibacterial and antifungal activity, where the growth of microbes was found to be inverse function of concentration of saponin. The MIC value for E.coli was found to be 260µg/mL and that of Staphylococcus aureus was 350µg/mL

Keywords: Ricinus communis, Triterpenoid saponin, Euphorbiaceae, Antimicrobial activity

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Ashutosh Srivastava

Chetna Dubey

Noor Khan