The Local Defect Resonance (LDR) approach is a technique which is used to detect and localize defects in structural components in a non-invasive way. In this contribution, we will assess whether the local resonance frequencies changes by altering a set of experimental testing conditions (i.e. imposed boundary condition, number of excitation points and excitation location). The specimen is made of a carbon fiber reinforced polymer and contains multiple flat bottom holes. However, here, we will focus on three detectable defects. The measured response analyzed through a parametric data-processing approach confirms that the local resonance frequencies are independent of the proposed changes.