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Efeito adjuvante de Zingiber Officinale L. em pacientes com câncer
1  Centro Paraibano de Oncologia


The Zingiber officinale popularly known as ginger or mangarataia, since antiquities is widely used for therapeutic and culinary purposes. Popularly used in infusions against colds, juices with fruits, in cooking in crystallized pieces, dehydrated, dried or powdered. The objective of this study is to discuss the use of the same as an adjuvant treatment in the control of emesis and nausea of ​​cancer patients under treatment. The mechanism of action of ginger responsible for the antiemetic activity, is not yet clear. Ginger has volatile oils, such as shogaol and gingerol which are its active chemical constituents. Studies in rats showed direct effect on the gastrointestinal tract and action on the Central Nervous System. Emesis and nausea are the main effects induced by cytotoxic drugs. According to reports in the literature, ginger has a promising antiemetic action as adjuvant therapy in cancer patients, bringing about the reduction of these symptoms and still acting with other beneficial effects such as anti-inflammatory, antioxidant, antimicrobial, anticoagulant, hypolipidemic and hypoglycemic. Its ideal use is in therapeutic doses recommended according to each patient profile and for limited periods, it would also enable the reduction of other conventional drugs, both the use of several drugs by the patient, as well as bring positive financial reflexes for the company. From this study we can observe the beneficial action of the use of medicinal plants, and may also emphasize the importance of investing in further studies and clinical trials, since there is no ginger-based medicine on the market.

Keywords: Ginger; ginger and cancer; antiemetic effects.