Urban expansion of cities has created a pressure on the territory, particularly in underdeveloped regions; agglomerating more population characterized by unequal and polarized social consolidation. Therefore, the social vulnerability of cities increases their degree of exposure to an event of natural origin, so they have to adjust in order to withstand or confront the negative impacts. In this sense, Mexico registers a seismic activity in three quarters of its territory; for example, on September 19, 7.1 degrees were presented on the Richter scale, where Morelos, Mexico, was one of the most affected States. This paper proposes to study the conditions of vulnerability of its population, prior to the earthquake, which allow to describe the affectation patterns and the self-management capacity that were used; Through the systematization of the process of organization and distribution of the University Collection Center (UCC). The information shows a social and economic vulnerability in the sites most affected by the earthquake, as well as a disarticulation of local forms of social reproduction. The resilience for cases like the one presented in Morelos, Mexico, implies the revision of the multidimensional vulnerability of the localities, but also the generation of a pre-and post-earthquake care strategy.