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Importance of HCN channels involved in various body conditions
Published: 03 July 2019 by MDPI in MOL2NET'19, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 5th ed. congress CHEMBIOMOL-05: Chem. Biol. & Med. Chem. Workshop, Bilbao-Lisboa, Portugal-Rostock, Germany, Galveston, Texas, USA, 2019
HCN channels play a variety of important functions in our body, this can be from the control in the heart rate as in the central and peripheral nervous system. This type of channel is voltage dependent and has a permeability to Na+ and K+, this permeability is usually controlled by the cAMP that is inside the cell. HCN channels participate in human diseases such as pain, heart failure, etc., and having a fundamental role in our body functions can offer new tools that allow the pharmaceutical industry to develop drugs, mainly analgesics.
Keywords: HCN channels, pain, inhibitors, new drugs, epilepsy.
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