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Approaching Resonant Absorption of Environmental Xenobiotics Harmonic Oscillation by Linear Structures
1 , 2 , * 3 , * 4
1  University of Medicine and Pharmacy of Craiova, Craiova, Romania
2  Military Institutes of University Education, Hellenic Naval Academy, Greece
3  Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, North Oshawa, Canada
4  Electrical Engineering Faculty, University of Craiova, Craiova, Romania

Published: 02 November 2011 by MDPI in The 1st World Sustainability Forum session Environmental Sustainability
Abstract: Over the last several decades, it has become increasingly accepted that the term xenobiotic relates to environmental impact, since environmental xenobiotics are understood to be substances foreign to a biological system, which did not exist in nature before their synthesis by humans. In this context, xenobiotics are persistent pollutants such as dioxins and polychlorinated biphenyls, as well as plastics and pesticides. Dangerous and unstable situations can result from the presence of environmental xenobiotics since their harmful effects on humans and ecosystems are often unpredictable. For instance, the immune system is extremely vulnerable and sensitive to modulation by environmental xenobitics. Various experimental assays could be performed to ascertain the immunotoxic potential of environmental xenobiotics, taking into account genetic factors, the route of xenobiotic penetration, and the amount and duration of exposure, as well as the wave shape of the xenobiotic. In this paper, we propose an approach for the analysis of xenobiotic metabolism using mathematical model and corresponding methods. This study focuses on a pattern depicting mathematically modelled processes of resonant absorption of a xenobiotic harmonic oscillation by an organism modulated as an absorbing oscillator structure. We represent the xenobiotic concentration degree through a spatial concentration vector, and we model and simulate the oscillating regime of environmental xenobiotic absorption. It is anticipated that the results could be used to facilitate the assessment of the processes of environmental xenobiotic absorption, distribution, biotransformation and removal within the framework of compartmental analysis, by establishing appropriate mathematical models and simulations.
Keywords: environmental xenobiotics , harmonic oscillation , mathematical model