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Nano-Ordered MCM-41-SO3H as a Heterogeneous and Efficient Catalyst for Synthesis of Bis(indolyl)methanes Under Solvent-Free Conditions
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1  Pharmaceutical and Biologically-Active Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran

Abstract: Nano-ordered MCM-41 anchored sulfonic acid (MCM-41-SO3H) was found to be an efficient catalyst for condensation of indoles with various carbonyl compounds to afford the corresponding bis(indolyl)methanes in high yields under solvent-free conditions using ball milling at room temperature.
Keywords: Nano-ordered MCM-41-SO3H, Solid Acid, Bis(indolyl)methanes, Solvent-Free Coditions, Ball-Milling, Green Chemistry