Abstract: The paper considers necessary conditions for establishing information science as a scientific autonomous discipline. The lack of commonly accepted definition of information is not as threatening as it may seem, as each study within the discipline may choose own definition, as well as own philosophical framework, when there are some alternatives to choose between. More important is development of common methodology of inquiry and some range of standard questions regarding the concept of information. Also, it is important to develop some standards of inquiry which would make information scientific studies accessible to philosophical analysis and reflection. In turn, contributions of information science to resolution of problems identified within philosophy will give a best measure of the maturity of information science as a discipline.