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Efficient synthesis of coumarin-chalcones hybrids as new scaffold with antibacterial interest
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1  Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782, Spain.
2  Departement of Microbiology and parasitology, CIBUS building-Faculty of Biology, Univesrsity of Santiago de Compostela, 15782, Spain.

Abstract: Due to the potential antibacterial activity of the chalcone and coumarin moieties, hybrid compounds containing both structures have been synthesized in good yield using the Knoevenagel reaction as the key step.
Keywords: Coumarin, Chalcone, Knoevenagel , Antibacterial