Please login first
New thiosemicarbazones based on quinoline scaffold as anticancer iron chelators
, * ,
1  University of Silesia, Institute of Chemistry, Szkolna 9, 40-007 Katowice, POLAND.

Abstract: Novel quinoline derivatives was designed as anticancer iron chelators. Structurally they combine active moieties of known quinoline and thiosemicarbazone bioeffectors. For the synthetic part of study we applied microvawe assisted techniques MAOS. Resulted compounds exhibited interesting anticancer activities against HCT116 cancer cells.
Keywords: Thiosemicarbazones, quinoline, anticancer, microwave