Please login first
Optimization of synthesis of dioctyl phthalate using response surface methodology
1 , 2 , 1
1  College of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
2  Department of Chemistry, Sharif University of Technology, P.O. Box 11155-3516, Tehran, Iran

Abstract: Esterification reaction of phthalic anhydride with 2-ethyl hexanol was investigated using sulfated titanium dioxide nano catalyst. The influence of reaction time, catalyst amount and alcohol/anhydride molar ratio was studied using a rotatable central composite design (CCD). The optimum values of factors were: 83 min for the time, 9 %wt catalyst, 9:1 alcohol:anhydride molar ratio. The maximum yield of 93% at optimum conditions was obtained.
Keywords: Optimization, Response surface methodology, Esterification, Dioctyl phthalate