Due to the potential antibacterial activity of the chalcone and coumarin moieties, hybrid compounds containing both structures have been synthesized in good yield using the Knoevenagel reaction as the key step.

In the frame of a biotinylation program of biologically active amines we synthesized two amides from 2-phenetylamine and 3,4-dimethoxybenzylamine, that were fully characterized by means of multinuclear NMR spectroscopy.

Presented work focuses on some detailed studies on enzymatic polysaccharide esterification. As a substrate a maize starch was used. Carboxylic acids with different aliphatic chains were the acylation agents and the process was carried out at different temperature, solvents and substrate: enzymes ratio. Obtained esters were analyzed according to the degree of substitution, degradation of polymer chains and changes in topography of modified starch granules. Obtained results shows that investigated method may be used for obtaining high substituted starches; however the DS strongly depends on the aliphatic chain of the acid.

In this paper microwave-assisted synthesis of a special catalyst, namely, Pt/C catalyst comprised of nanoparticles is discussed. Owing to its unique characteristics, the catalyst is very beneficial to the performance of proton exchange membrane fuel cells (PEMFCs). As mentioned in the article, Pt nanoparticles once integrated with Carbon, provide better catalytic activity/stability. Such integration has been achieved successfully by microwave heating. The relevant experimental works of some researchers are briefly reviewed in the end.

The molecular recognition features of urea derivatives including (+)-biotin methyl ester with hosts containing 2,6-bisamidopyridine or 2,5-bisamidopyrrole bearing pyridyl or 1,8-naphthyridyl groups have been studied by Monte Carlo (MC) conformational search. The most probable conformation and the associated energy of the complexes have been obtained.

A new and flexible route for the asymmetric synthesis of a variety of alkylated bridged tetrahydro-2-benzazepines has been developed. The key steps are the highly diastereoselective Michael addition of metalated SAMP-hydrazones to α,β-unsaturated esters combined with cyclomethylenation/Mitsunobu coupling reactions to secure the formation of the seven-membered azaheterocycle and of the bridged unit respectively.

1,2-Cyclic sulfamidates undergo novel, efficient and regiospecific intramolecular nucleophilic cleavage with aryllithiated species to provide an entry to poly, diversely and enantiopure N-substituted benzosultams.

A series of cis-locked stilbenic compounds related to combretastatin and combretastatin A4 has been designed and synthesized. The cytotoxic effects of these rigid analogues were evaluated as well as their abilities to inhibit tubulin polymerization.

The 1,3-dipolar cycloaddition (1,3-DC) and Diels-Alder (DA) reactions of substituted pyridinium-3-olates and pyrazinium-3-olates with methyl acrylate are studied using DFT method at the B3LYP/6-31G(d) level of theory. The molecular mechanism of the possible stereo- and regiochemical pathways is characterized both in the condensed and solvent phases. It is found that 1,3-DC is the favourable pathway for the reaction of pyridinium-3-olates with methyl acrylate and the thermodynamically more stable 6-substituted 8-azabicyclo[3.2.1]oct-3-en-2-ones are formed preferentially. This research is further extended to substituted pyrazinium-3-olates. Reactions of unsubstituted pyrazinium-3-olate and 1-methyl pyrazinium-3-olate with both ethene and methyl acrylate show a preference for the DA cycloaddition reaction. However, the addition of methyl acrylate to substituted pyrazinium-3-olates results in competitive mechanistic pathways and the preferred cycloaddition pathway is dependent on the location of the methyl group on the pyrazinium ring. The presence of a methyl substituent on C5 of the pyrazinium-3-olate favours the 1,3-DC over the DA reaction as the 2,6 positions are not sterically crowded. However, when methyl groups are present at the C2 and C6 positions, cycloaddition occurs via a Diels-Alder route which is free from encumbrance and hence bond formation at the C5 position is more enhanced.

Mesoporous Borosilicate (B-MCM-41) efficiently catalyzed the three-component Strecker-type reaction of different amines and aldehydes or ketones with trimethylsilyl cyanide (TMSCN) in CH₂Cl₂ at room temperature to afford the corresponding α-aminonitriles in excellent yields. The catalyst can be recovered and reuse for at least 5 reaction cycles without significant lose of its reactivity.