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The 1st International Online Conference on Bioengineering

Bioengineering in a Generative AI World

Part of the 1st International Online Conference on Bioengineering series
16–18 Oct 2024
Event's Timezone: Central European Summer Time
Abstract Submission Deadline
17th July 2024
Abstract Acceptance Notification
17th August 2024

Registration Deadline
10th October 2024

Bioelectronics, Translational Bioengineering, Biochemical Engineering and Applications, Biomolecular Cellular Tissue Engineering and Applications, Bionics and Biological Cybernetics, Bioprocess and Biosystems Engineering and Applications
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Announcements:

Program Overview is Online!
Submissions closed!

IOCBE 2024 is free to join, secure your spot today! #REGISTER NOW!

Keep an eye out for more updates and announcements about the event!

Welcome from the Chairs

Dear Colleagues,

In celebration of its tenth anniversary, Bioengineering will host its first International Online Conference on 16-18 October 2024. It is my pleasure to announce and extend this open invitation for you to participate.

With a theme of Bioengineering in a Generative AI World, the conference will feature presentations from distinguished scholars at the nexus of engineering and clinics, engineering and food, engineering and industry, and innovations in bioengineering education. Our conference sessions will following the main sections of our journal with specific attention to:

  1. Regenerative and Tissue Engineering;
  2. Biomechanics and Sports Medicine;
  3. Biomedical Biomaterials;
  4. Nano-Biotechnology;
  5. Biosignal Processing;
  6. Biochemical Engineering.

This conference, organized and hosted by MDPI Bioengineering, will bring together scientists, engineers, and practitioners from different areas to discuss the important recent developments in bioengineering, including bioengineered foods, allotransplantation, multi-omics, theragnostics and bioengineering convergence.

It will represent a great opportunity for the virtual meeting of the interdisciplinary community, aiming to discuss the important breakthroughs in fundamental science undergirding bioengineering, bioengineering technology, and its impact fields in food, industry, environment and animal and human health.

This conference will be a celebration of the contributions of Bioengineering and will feature three awards given for the Best Oral Presentation and Best Poster presented at the conference.

We look forward to your participation.

Kind regards,
Prof. Dr. Anthony Guiseppi-Elie
Founding Editor-in-Chief, Bioengineering
Founding Dean of Engineering, Anderson University SC
President and Sr. Fellow, AIIMSEI

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Program Overview

16th October 2024

17th October 2024

18th October 2024

Welcome and Opening Remarks Convening Chair
(09
:00 CEST|03:00 EDT|15:00 CST)




Plenary Talk
(09:10 CEST|03:10 EDT|15:10 CST)
Plenary Talk
(09:10 CEST|03:10 EDT|15:10 CST)
Plenary Talk
(09:10 CEST|03:10 EDT|15:10 CST)

Keynote Talks
(09:45 CEST|03:45 EDT|15:45 CST)

Keynote Talks
(09:45 CEST|03:45 EDT|15:45 CST)

Keynote Talks
(09:45 CEST|03:45 EDT|15:45 CST)
Session 1. Regenerative and Tissue Engineering (Invited and Contributed Oral Presentations)
(10:25 CEST|04:25 EDT|16:25 CST)
Session 3. Biomedical Materials (Invited and Contributed Oral Presentations)
(10:25 CEST|04:25 EDT|16:25 CST)
Session 5. Biosignal Processing (Invited and Contributed Oral Presentations)
(10:25 CEST|04:25 EDT|16:25 CST)
Break
(50 min)

Break
(30 min)

Bioengineering Lectureship Award
(12:25 CEST|06:25 EDT|18:25 CST)

Break
(50 min)
Keynote Talks
(12:50 CEST|06:50 EDT|18:50 CST)
Keynote Talks
(12:50 CEST|06:50 EDT|18:50 CST)
Keynote Talks
(12:50 CEST|06:50 EDT|18:50 CST)
Session 2. Biomechanics and Sports Medicine (Invited and Contributed Oral Presentations)
(13:30 CEST|07:30 EDT|19:30 CST)
Session 4. Nano-Biotechnology (Invited and Contributed Oral Presentations)
(13:30 CEST|07:30 EDT|19:30 CST)
Session 6. Biochemical Engineering (Invited and Contributed Oral Presentations)
(13:30 CEST|07:30 EDT|19:30 CST)
Plenary Talk
(15:00 CEST|09:00 EDT|21:00 CST)
Plenary Talk
(15:00 CEST|09:00 EDT|21:00 CST)
Plenary Talk
(15:00 CEST|09:00 EDT|21:00 CST)
Closing Remarks/ Awards Ceremony
Convening Chair
(15:30 CEST|09:40 EDT|21:40 CST)

* CEST - Central European Summer Time
EDT -
Eastern Daylight Time
CST -
China Standard Time

IOCBE 2024 Program (DAY1)

IOCBE 2024 Day 1

Session 1. Regenerative and Tissue Engineering

Date: 16th October 2024 (Wednesday)
Time: 9:00 (CEST, Basel) | 03:00 (EDT, New York) | 15:00 (CST Asia, Beijing)

Time
(CEST)
Speaker Title
09:00-09:10 Prof. Dr. Anthony Guiseppi-Elie
Convening Chair
Welcome and Opening Remarks

09:10-09:40

Prof. Dr. Wai Yee Yeong
(NTU, Singapore)
Plenary Speaker

3D Printing and Biofabrication: Progress and Opportunities for Machine Learning in Materials and Processes
09:40-09:45 Prof. Dr. Elena Jones
(ULeeds, UK) and
Prof. Dr. Dimitrios Kouroupis
(UMiami, USA)
Welcome by Session Chairs

09:45-10:05 Dr. Dominik Egger
(UoH, Germany)
Keynote Speaker
Advanced Cell Culture Technologies for Mesenchymal Stem Cell-Based Therapies
10:05-10:25 Dr. Jonathan P. Wojciechowski
(Oxford, UK)
Keynote Speaker
Post-printing functionalisation of 3D printed hydrogels as a modular biomaterials platform
Invited and Contributed Oral Presentations Session 1: Regenerative and Tissue Engineering
10:25-10:40 Prof. Dr. Gulden Camci-Unal
(UMass, Lowell, USA)
Invited Speaker
Unconventional Biomaterials for Tissue Engineering and Regenerative Medicine
10:40-10:55 TO BE DETERMINED TO BE DETERMINED
10:55-11:10 Nikitha Pandian
(Uamity, India)
Selected Speaker
Green Tech in Medicine: Scenedesmus obliquus-reinforced composite Hydrogels for Wound Therapy
11:10-11:25 Alexey Dudaev
(SFU, Russia)
Selected Speaker
Three-dimensionally Printed Porous Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Scaffold for Bone Regeneration: Fabrication, in Vitro and in Vivo Studies
11:25-11:40

George Skepastianos
(EANP, Greece)
Selected Speaker

Efficient decellularization of full-thickness abdominal wall scaffold to produce a potential tissue-engineered product
11:40-11:55 Marcelo Santos
(UFRGS, Brazil)
Selected Speaker
Neural differentiation of mesenchymal cells after 3D bioprinting using a decellularized spinal cord-based biomaterial
11:55-11:45 Break

Session 2. Biomechanics and Sports Medicine

Date: 16th October 2024 (Wednesday)
Time: 12:45 (CEST, Basel) | 06:45 (EDT, New York) | 18:45 (CST Asia, Beijing)

Time
(CEST)
Speaker Title
12:45-12:50 Prof. Dr. Franz Konstantin Fuss
(UBT, Germany)
Dr. Michael Moreno
(TAMU, USA)
Welcome by Session Chairs

12:50-13:10 Prof. Dr. Nicola Hagemeister
(ETS, Canada)
Keynote Speaker
Kinematic Assessment of the Knee Joint
13:10-13:30 Dr. Rene Ferdinands
(USydney, Australia)
Keynote Speaker
Assessing Bowling Legality in Cricket: Biomechanical Insights and Implications
Invited and Contributed Oral Presentations Session 2: Biomechanics and Sports Medicine
13:30-13:45 Prof. Dr. Franz Konstantin Fuss
(UBT, Germany)
Invited Speaker
Dynamic balance diagnostics with smart insoles
13:45-14:00 Dr. Daria Podstawczyk
(WUST, Poland)
Invited Speaker
Coaxial 4D Printing of Thermoresponsive Hydrogel Soft Bioactuators with Embedded Perfusable Channels
14:00-14:15 Fotios Zisis
(UoP-Sparta, Greece)
Selected Speaker
Similar Spatiotemporal Parameters of Gait between Children with Typical Development and Autism Spectrum Disorder
14:15-14:30 Nefeli Maria Tsirmpini
(UPeloponnese, Greece)
Selected Speaker
Quantitative data to evaluate Clinical Pilates efficacy in chronic low back pain using inertial measurement units
14:30-14:45 Simone Marino
(Ud’A, Italy)
Selected Speaker
Impact of Box Squats and Pin Squats on Powerlifting Performance: An Electromyographic Analysis
14:45-15:00 Dr. Andrew Robbins
(UTTyler, USA) and
Dr. Michael Moreno
(TAMU, USA)
Invited Speakers
Learning how Sheep Move: Developing a General Inverse Kinetic Model for Sheep
15:00-15:30 Prof. Dr. Kristala L. Jones Prather
(MIT, USA)
Plenary Speaker
Biosensor-Guided Regulation of Metabolic Pathways

IOCBE 2024 Program (DAY2)

IOCBE 2024 Day 2

Session 3. Biomedical Materials

Date: 17th October 2024 (Thursday)
Time: 9:00 (CEST, Basel) | 03:00 (EDT, New York) | 15:00 (CST Asia, Beijing)

Time
(CEST)
Speaker Title

09:10-09:40

Prof. Dr. Chuanbin Mao
(CUHK, Hong Kong)
Plenary Speaker

Phage-Based Biomaterials, Nanomedicine and Regenerative Medicine
09:40-09:45 Prof. Dr. Gary Bowlin
(UMemphis, USA) and
Prof. Dr. Archana Bhaw-Luximon
(UM, Mauritius)
Welcome by Session Chairs

09:45-10:05 Prof. Dr. Archana Bhaw-Luximon
(UM, Mauritius)
Keynote Speaker
Biomaterials addressing health and climate change challenges
10:05-10:25 Prof. Dr. Gary L. Bowlin
(UMemphis, USA)
Keynote Speaker
Near-field Electrospinning Use in Fabricating the Next-generation Vascular Grafts
Invited and Contributed Oral Presentations Session 3: Biomedical Materials
10:25-10:40 Prof Dr Seda Kizilel
(KoçU, Turkey)
Invited Speaker
Designing Immunologically Invisible Spheroids Using Biomaterials, Genetic Engineering and Machine Learning
10:40-10:55 Amina Voznyuk
(MISIS, Russia)
Selected Speaker
Layer-by-layer assembly for manufacturing local chemotherapy platforms with controlled and sustained drug release to prevent local tumor relapse
10:55-11:10 Bani Preet Kaur
(Uamity, India)
Selected Speaker
The Role of Zinc Metal–Organic Framework (Zn-MOF) in Augmenting Anti-Mycobacterial Drug Action
11:10-11:25 TO BE DETERMINED TO BE DETERMINED
11:25-11:40

Elizaveta Sergeevna Permyakova
(MISIS, Russia)
Selected Speaker

Superabsorbent Curdlan–Chitosan Foams with Bioactive Additives for Healing Wounds
11:40-11:55 Elisa Roldan Ciudad
(MMU, UK)
Selected Speaker
Combining machine learning and musculoskeletal models: A novel route to optimise the manufacturing of biomimetic ligament implants.
11:55-11:45 Break

Session 4. Nano-Biotechnology

Date: 17th October 2024 (Thursday)
Time: 12:45 (CEST, Basel) | 06:45 (EDT, New York) | 18:45 (CST Asia, Beijing)

Time
(CEST)
Speaker Title
12:25-15:45

Bioengineering Lectureship Award
Presentation

12:45-12:50 Dr. Gary Chinga Carrasco
(RISE PFI, Norway)
Welcome by Session Chairs

12:50-13:10 Prof. Dr. Pedro Fardim
(KULeuven, Belgium)
Keynote Speaker
Biopolymers and Bio-hybrids for Health and Care
13:10-13:30 Prof. Dr. Anthony Guiseppi-Elie (TAMU, USA)
Keynote Speaker
Modeling a Multi-modal Biochip for Physiological Status Monitoring in the Triage of Hemorrhagic Trauma and for Allograft Stratification
Invited and Contributed Oral Presentations Session 4: Nano-Biotechnology
13:30-13:45 Dr. Hana Lísalová
(FZU-CAS, Czech Republic)
Invited Speaker
Advancing Cell-on-a-Chip Interfaces with Bio-functional Terpolymer Nano-Brushes Exhibiting Strong Resistance to Bacteria
13:45-14:00 Dr. Eduardo Espinosa
(UCordoba, Spain)
Invited Speaker
Biopolymers and 3D Bioprinting
14:00-14:15 Rupal Kaushik
(IIT, India)
Selected Speaker
Biocompatible Surface-Modified MoS2 Nanoflowers for Antibacterial Applications: Unravelling the Mechanistic Insights
14:15-14:30 Etelka Chung
(UH, UK)
Selected Speaker
Development of antimicrobial PDMS polymers containing Silver-Copper Nanoparticles for potential applications in biomedical devices
14:30-14:45 Lyubomira Radeva
(MUS, Bulgaria)
Selected Speaker
The encapsulation of oregano oil in natural nanogels and preliminary studies on its antiviral activity
14:45-15:00 Shichao Ding
(UCSanDiego, USA)
Invited Speakers
Rational Design of Single-Atom Nanozymes for Biomedical Applications
15:00-15:30 Prof. Dr. Luke P. Lee
(Harvard, USA)
Plenary Speaker
Nanomedicine via Quantum Plasmonic SANDs, EXODUS, and Brain Organoid MAP

IOCBE 2024 Program (DAY3)

IOCBE 2024 Day 3

Session 5. Biosignal Processing

Date: 18th October 2024 (Friday)
Time: 9:00 (CEST, Basel) | 03:00 (EDT, New York) | 15:00 (CST Asia, Beijing)

Time
(CEST)
Speaker Title

09:10-09:40

Prof. Dr. Tingrui Pan
(USTC, China)
Plenary Speaker

The Rise of Flexible Iontronics for Medical Intelligence
09:40-09:45 Prof. Dr. Andrea Cataldo
(USalento, Italy) and
Prof. Dr. Egidio De Benedetto
(UNaples Federico II, Italy)
Welcome by Session Chairs
09:45-10:05 Prof. Dr. Selim Bozkurt
(UU, UK)
Keynote Speaker
Detection of Cardiovascular Disorders in Patients Supported with Continuous-Flow Left Ventricular Assist Devices by Monitoring Electrical Current Signals
10:05-10:25 Prof. Dr. Leopoldo Angrisani
(UNFII, Italy)
Keynote Speaker
Biosignal-based human-machine interfaces: a metrological approach to performance characterization
Invited and Contributed Oral Presentations

Session 5: Biosignal Processing

10:25-10:40 Daniela Pedrozo Roca
(INIBIO, UNSJ, Argentina)
Invited Speaker
Functional Characterization of Brain Areas Using Functional Magnetic Resonance Imaging
10:40-10:55 Martim G. Silva
(UCP, Portugal)
Selected Speaker
Speech Non-Linear Multiband-Time-Series Analysis for Detecting Alzheimer’s Disease
10:55-11:10 Anton Gerasimov
(NSTU, Russia)
Selected Speaker
Effect of Individual Abilities for Mental 3D Rotation in Learning EEG-Controlled BCIs"
11:10-11:25 Mariano Jose Guillen
(NUT-FACET, Argentina)
Selected Speaker
Exploratory simulation study on high-frequency detection of cell internal structures
11:25-11:40

Svitlana Tymetska
(JU, Poland)
Selected Speaker

Poly(vinyl pyridine) coatings cross-linked with Cu or Zn as active layers for biosensors that are sensitive to protein adsorption and cell adhesion
11:40-11:55 Joana Pinto
(UPT, Portugal)
Selected Speaker
Mapping Decision-Making Traits through EEG-Derived Personality Profiles
11:55-11:45 Break

Session 6. Biochemical Engineering

Date: 18th October 2024 (Friday)
Time: 12:45 (CEST, Basel) | 06:45 (EDT, New York) | 18:45 (CST Asia, Beijing)

Time
(CEST)
Speaker Title
12:45-12:50 Prof. Dr. Liang Luo
(HUST, China)
Welcome by Session Chairs

12:50-13:10 Prof. Dr. Carmen C. Mayorga Martinez
(UPC, Peru)
Keynote Speaker
Functional Materials to Obtain Smart Microrobotics for Diagnostics and Therapy
13:10-13:30 Prof. Dr. Maria Teresa Fernandez Abedul
(UOviedo, Spain)
Keynote Speaker
Development of bioelectrochemical platforms for decentralized and low-cost analysis of molecules of interest in clinical, food or environmental fields
Invited and Contributed Oral Presentations Session 6: Biochemical Engineering
13:30-13:45 Prof. Dr. Silviya Petrova Zustiak
(SLU, USA)
Invited Speaker
Development of Super-Lubricious Hydrogel Microspheres for the Treatment of Knee Osteoarthritis
13:45-14:00 Stephanie Klinghammer
(TUD, Germany)
Selected Speaker
Development of intraoral sensors for the continuous measurement of clinically relevant parameters in the oral cavity
14:00-14:15 Hakan Çelebi
(AU, Turkey)
Selected Speaker
Current perspectives on the applicability of lignin material in the biosorption process
14:15-14:30 Carla Goy
(NUT-FACET, Argentina)
Selected Speaker
Alternative methods for low-cost microfluidic device fabrication
14:30-14:45 Harshavardhan Reddy Borra
(YVU, Inadia)
Invited Speakers
Enhancing biomanufacturing efficiency: A model-based plug-and-play Hybrid fed-batch process using ATF perfusion for high-yield drug substance production
14:45-15:00 Antonio D’Ambrosio
(UCBM, Italy)
Selected Speaker
Prediction of drug transport, distribution, and absorption by a multicompartmental physiologically based pharmacokinetic model
15:00-15:30 Prof. Dr. Molly Shoichet
(UToronto, Canada)
Plenary Speaker
Overcoming Barriers: Local Cell & Therapeutic Delivery to the Central Nervous System

15:30-15:40 Prof. Dr. Anthony Guiseppi-Elie
Convening Chair
Closing Remarks/ Awards Ceremony

Event Chairs

Founding Editor-in-Chief, Bioengineering,
Founding Dean of Engineering, Anderson University SC,
President and Sr. Fellow, AIIMSEI

Introduction
Bio
Prof. Dr. Anthony Guiseppi-Elie is an international medical sciences, engineering, and innovation consultant at the American International Institute of Medical Sciences, Engineering, and Innovation. A former Vice President and Chief Academic Officer at Tri-County Technical College. He has 15 years of industrial research and product development experience and 18 years of experience as a tenured, titled, and endowed full professor at universities that include Virginia Commonwealth University, Clemson University, Texas A&M University, and Anderson University, where he was the Founding Dean of the College of Engineering. He has been associated with three startup companies and is Founder, President, and Scientific Director of ABTECH Scientific, Inc. A US citizen who was born in Trinidad and Tobago, he holds the Sc.D. in Materials Science and Engineering from MIT, the M.Sc. in Chemical Engineering from the University of Manchester (UMIST), and the B.Sc. (First Class Honors) in Applied, Analytical, and Biochemistry from the University of the West Indies (UWI). He has published over 225 peer-reviewed journal articles, holds 8 patents, and is a fellow of IEEE, AIMBE, BMES and the RSC. His research interests are in physiological monitoring during hemorrhagic trauma and allotransplantation, polymeric nanobiomaterials in drug delivery and tissue regeneration, and microanalytical systems in the service of human health and medicine.

Media and Interfaces Laboratory (LAMEIN), Bioengineering Department, Faculty of Exact Sciences and Technology (FACET), National University of Tucumán, Superior Biological Research Institute (INSIBIO), CONICET, Argentina

Introduction
Bio
Rossana Madrid is EE and Ph.D. in Bioengineering. She is currently a Full Professor of Biomedical Transducers and Biosensors and Microsystems in the Biomedical Engineering Program, and also at a Doctoral degree, from the Faculty of Exact Sciences and Technology at the University of Tucumán, Argentina. She is Principal Researcher at the National Council of Scientific and Technical Research of Argentina (CONICET) and she leads the Biosensors and Microsystems group. She has published R&D papers in national and international journals, two book chapters, and has developed four patents. She leads research grants and international cooperation grants with German Universities. Her main research fields include sensors and biosensors, microfluidic systems, and paper-based POC devices for biomedical and environmental applications.

Session Chairs

Dr. Elena A. Jones

Leeds Institute of Molecular Medicine, School of Medicine, University of Leeds, Leeds, UK

Prof. Dr. Gary L. Bowlin

Department of Biomedical Engineering, The University of Memphis, Memphis, USA

Prof. Dr. Franz Konstantin Fuss

1. Chair of Biomechanics, Faculty of Engineering Science, University of Bayreuth, Bayreuth, Germany 2. Division of Biomechanics, Department of Biomechatronic Systems, Fraunhofer Institute of Manufacturing Engineering and Automation IPA, Stuttgart, Germany

Prof. Dr. Michael Moreno

Department of Mechanical Engineering, J. Mike Walker ’66 Faculty, Texas A&M University, Texas, USA.

Dr. Gary Chinga Carrasco

RISE PFI, Høgskoleringen 6b, Trondheim, Norway

Dr. Andrea Cataldo

Department of Innovation Engineering (DII), University of Salento, Lecce, Italy

Prof. Dr. Liang Luo

College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

Dr. Dimitrios Kouroupis

Department of Orthopaedics, Miller School of Medicine. University of Miami, Miami, USA.

Dr. Egidio De Benedetto

Department of Information Technology and Electrical Engineering, University of Naples Federico II, Naples, Italy.

Event Committee Members

Department of Mechanical Engineering, National Chung-Hsing University, Taichung, Taiwan.

Nanotechnology Innovation Center Kansas State (NICKS), Kansas State University, Manhattan, USA.

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Center for Surgical Bioengineering, University of California Davis, CA, USA.

School of Materials Science and Engineering, Nanyang Technological University, Singapore City, Singapore.

School of Mechanical & Manufacturing Engineering, Dublin City University, Dublin, Ireland.

Department of Cardiothoracic Surgery, Stanford University School of Medicine, California, USA.

Faculty of Engineering, University Campus Biomedico of Rome, Rome, Italy

Department of Bioscience Research, Department of Medicine, Department of Microbiology, Immunology and Biochemistry, The University of Tennessee Health Science Center, Memphis, TN, USA

Biotechnology Institute for Cell and Tissue Culture Technologies, University of Natural Resources and Life Sciences Vienna, Vienna, Austria

Department of Mechanical Engineering and Engineering Science, University of North Carolina at Charlotte, Charlotte, NC, USA.

Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, USA

Irma Lerma Rangel School of Pharmacy, Texas A&M Health Science Center, Texas A&M University, College Station, TX , USA.

Centre for Advanced Biomedical Imaging (CABI), Department of Medicine, University College London, London, UK.

Department of Innovative Technologies in Medicine & Dentistry, "G. D'Annunzio" University of Chieti–Pescara, Italy.

Human Histology & Embryology Section, Department of Surgery, Dentistry, Paediatrics & Gynaecology, University of Verona Medical School, Verona, Italy.

Department of Biological Sciences, Oakland University, Rochester, USA.

Stem Cell Core, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, USA.

Department of Mechanical Engineering, University of Kansas, Lawrence, USA.

School of Life Science and Biotechnology, Dalian University of Technology, Dalian, China.

Department of Biomedical Engineering, College of Engineering, University of Miami, Coral Gables, FL, USA.

Physics department, Faculty of Science, University of Lisbon, Lisbon, Portugal.

School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough, UK.

The Mucosal Immunology & Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, Republic of Korea.

Department of Rehabilitation Medicine, Tongji University School of Medicine, Shanghai, China.

NOVA Medical School, Faculty of Medical Sciences, New University of Lisbon, Lisbon, Portugal.

Department of Bioengineering, Faculty of Engineering, Ege University, Izmir, Turkey.

Department of Information Engineering, Marche Polytechnic University, Ancona, Italy.

Department of Information Engineering, Marche Polytechnic University, Ancona, Italy.

Department of Chemistry, The Hong Kong University of Science and Technology, HKSAR, Pokfulam, Hong Kong.

Department of Electrical and Information Engineering (DEI), Polytechnic University of Bari, Bari, Italy.

Plenary Speakers

Harvard Medical School, Harvard University, Brigham and Women's Hospital, Boston, USA.,
[13:00 Coordinated Universal Time (UTC) | 17 Oct 2024 (Thursday)]

Introduction
Talk
Nanomedicine via Quantum Plasmonic SANDs, EXODUS, and Brain Organoid MAP. Abstract: In this presentation, I will report on the importance of human exosomes in both diagnostics and therapeutics. First, I will report the advancements in applications of the EXODUS (EXOsome Detection via the Ultrafast-purification System) for the quick, pure, and automated label-free purification of exosomes from various biofluids. We have made significant progress in purifying exosomes from cancer patients' urine samples, facilitating efficient multiomics analysis. Additionally, our iTEARS (integrated Tear Exosome Analysis via Rapid-isolation System) identifies protein and RNA biomarkers, enabling predictive, preventive, personalized diagnosis of various diseases by analyzing a teardrop. I will also discuss the development of a patient-derived brain organoid MAP (Microphysiological Analysis Platforms) using iPSCs to form brain organoids to simultaneously detect and deliver EVs (extracellular vesicles) and EBs (electrophysiological brainwaves) from brain organoids. We aim to understand the connection between molecular and neurophysiological expressions and discover efficient biomarkers. Through in vitro models of the human brain MAP, we strive to address fundamental questions of neuropathogenesis, find solutions for neurodegenerative diseases, and explore potential therapeutic options for precision medicine by systematically studying the dynamics of EVs and EBs. Our collaborative efforts to create EXODUS, iTEARS, and brain organoid MAPs are paving the way for the 4Ps (predictive, preventive, personalized, participative) of precision medicine.
Bio
Luke P. Lee is a Professor at Harvard Medical School. He received his BA and PhD in from UC Berkeley. He joined the faculty at UC Berkeley in 1999 after more than a decade of industry experience. He became the Arnold and Barbara Silverman Distinguished Professor and the Lester John and Lynne Dewar Lloyd Distinguished Professor at Berkeley. He also served as the Chair Professor in Systems Nanobiology at ETH Zürich. He founded the Biomedical Institute for Global Healthcare Research & Technology (BIGHEART). He served as Associate President for International Research and Innovation and Tan Chin Tuan Centennial Professor at the National University of Singapore. He also founded the Institute for Quantum Biophysics at Sungkyunkwan University, Korea. He has authored over 350 research articles, contributed to four book chapters, and holds 60 international patents. He has been honored as a Fellow of the Royal Society of Chemistry and the American Institute of Medical and Biological Engineering. He has received numerous awards, including the IEEE William J. Morlock Award, NSF Career Award, Fulbright Scholar Award, and the HoAm Prize.

Institute of Biomedical Engineering, University of Toronto, Toronto, Canada.,
[13:00 Coordinated Universal Time (UTC) | 18 Oct 2024 (Friday)]

Introduction
Talk
Overcoming Barriers: Local Cell & Therapeutic Delivery to the Central Nervous System. Abstract: We are particularly interested in regeneration in the central nervous system after traumatic injury or disease such as spinal cord injury, stroke and blindness. After traumatic injury to the central nervous system, a glial scar forms which limits both degeneration and regeneration. To promote the latter, we (and others) have been investigating chondroitinase ABC; however, the impact of this potent enzyme has been limited by its delivery and its inherent instability. We invented an affinity-release system and a more stable, mutated chondroitinase ABC, which we have been investigating in the context of spinal cord injury and stroke. For stroke, we have also been interested in endogenous stem cell stimulation, which we have been pursuing in collaboration with Cindi Morshead’s laboratory. With local delivery, we are able to release factors directly to the brain to modulate the immune system, stimulate tissue repair and functional recovery. In blindness due to age-related macular degeneration, the cells at the back of the eye - the photoreceptors and the retinal pigmented epithelium - die. In order to stop and reverse blindness, these cells need to be replaced, yet finding a source of these cells is in itself difficult. In collaboration with Prof Derek van der Kooy’s lab, we investigated the co-transplantation of both photoreceptors and retinal pigmented epithelium using an injectable hydrogel, which has shown to enhance cell survival, leading to some functional repair. Fascinatingly, this hydrogel impacts the recently discovered phenomenon of material transfer, which we are pursuing in collaboration with Valerie Wallace’s lab. While mouse photoreceptors were known to transfer material, it wasn’t until our recent study that we realized that human photoreceptors can also transfer material, opening up new possibilities for stem cell transplantation.
Bio
Professor Molly Shoichet is University Professor, a distinction held by less than 2% of the faculty, at the University of Toronto. She served as Ontario’s first Chief Scientist in 2018 where she worked to enhance the culture of science. Dr. Shoichet has published over 800 papers, patents and abstracts and has given over 580 lectures worldwide. She currently leads a laboratory of 30 and has graduated 260 researchers. Her research is focused on drug and cell delivery strategies in the central nervous system (brain, spinal cord, retina) and 3D hydrogel culture systems to model cancer. Dr. Shoichet co-founded four spin-off companies, is actively engaged in translational research and science outreach. Dr. Shoichet is the recipient of many prestigious distinctions and the first person to be inducted into all three of Canada’s National Academies of Science of the Royal Society of Canada, Engineering and Health Sciences. In 2018, Professor Shoichet was inducted as an Officer of the Order of Canada and in 2011, she was awarded the Order of Ontario. Dr. Shoichet was the L’Oreal-UNESCO For Women in Science Laureate for North America in 2015, elected Foreign Member of the US National Academy of Engineering in 2016, won the Killam Prize in Engineering in 2017 and elected Fellow to the Royal Society (UK) in 2019. In 2020, Dr. Shoichet was awarded the NSERC Herzberg Gold Medal and won the Margolese National Brain Disorders Prize. In 2022, Dr. Shoichet was elected Fellow of the US National Academy of Inventors. Dr. Shoichet received her SB from the Massachusetts Institute of Technology (1987) and her PhD from the University of Massachusetts, Amherst in Polymer Science and Engineering (1992).

School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore.,
[7:10 Coordinated Universal Time (UTC) | 16 Oct 2024 (Wednesday)]

Introduction
Talk
3D Printing and Biofabrication: Progress and Opportunities for Machine Learning in Materials and Processes. Abstract: In recent years, machine learning (ML) technologies have been widely adopted to explore complex relationships among various parameters in different 3D printing techniques and biofabrication processes . These ML models are adept at identifying intricate patterns from large, well-organized datasets, thereby revealing hidden insights crucial for making informed decisions during the 3D printing process. The collaborative integration of ML and 3D Printing has the potential to transform the design and production of biotechnology parts. This talk discusses the challenges and opportunities arising at the intersection of these two dynamic fields.
Bio
Professor Yeong is Professor of Mechanical Engineering in the School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore. Professor Yeong’s research work focuses on 3D bioprinting, as well as 3D printing of functional materials. She has attracted more than SGD$15M in research grants and published more than 180 papers. She has been recognized with multiple awards including Top 50 Asia Women Tech Leaders 2024, NRF Investigatorship Class of 2022, Singapore 100 Women in Tech (SG100WIT) 2021 and the Inaugural TCT Woman in 3D Printing Award 2019. She is listed in the Top 2% Scientists Worldwide in a study from Stanford University since 2021, and named Clarivate Highly Cited Researcher 2022.

Head of the Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, USA.,
[13:00 Coordinated Universal Time (UTC) | 16 Oct 2024 (Wednesday)]

Introduction
Talk
Biosensor-Guided Regulation of Metabolic Pathways. Abstract: Microbial systems offer the opportunity to produce a wide variety of chemical compounds in a sustainable fashion. Economical production, however, requires processes that operate with high titer, productivity, and yield – and that, preferably, minimize the number of material inputs to the system. Transcription factor-based biosensors provide an opportunity to utilize existing substrates as inducers for pathway genes. The specificity of these biosensors also enables “switch-like” behavior, in which certain pathways can be activated only in the presence of their associated substrates. We have leveraged previous work in autonomous regulation of metabolic pathways to establish a paradigm for substrate-mediated activation of biosynthetic pathways. This approach is particularly interesting in the context of mixed substrate feeds with variable composition. I will discuss our group’s efforts to build, characterize, and deploy biosensors for substrate-regulated control of biosynthesis.
Bio
Prof. Dr. Kristala L.J. Prather is the Arthur D. Little Professor and Department Head in the Department of Chemical Engineering at MIT. She received an S.B. degree from MIT in 1994 and Ph.D. from the University of California, Berkeley (1999), and worked 4 years in BioProcess Research and Development at the Merck Research Labs prior to joining the faculty of MIT. Her research interests are centered on the design and assembly of recombinant microorganisms for the production of small molecules, with additional efforts in novel bioprocess design approaches. Prather’s honors include the Charles Thom Award of the Society for Industrial Microbiology and Biotechnology (2017), the Andreas Acrivos Award for Professional Progress in Chemical Engineering of the American Institute of Chemical Engineers (AIChE, 2021), and the Marvin J. Johnson Award (BIOT Division, American Chemical Society, 2024). Additional honors include selection as a Fellow of the Radcliffe Institute for Advanced Study (2014-2015), the American Association for the Advancement of Science (AAAS; 2018), the American Institute for Medical and Biological Engineering (AIMBE; 2020), and AIChE (2020).

Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong.,
[7:10 Coordinated Universal Time (UTC) | 17 Oct 2024 (Thursday)]

Introduction
Talk
Phage-Based Biomaterials, Nanomedicine and Regenerative Medicine. Abstract: Bacteriophages, also called phages, are human-safe non-toxic viruses that specifically infect bacteria. They are one of the most common and diverse entities in biospheres. They can be pictured as nanobiomaterials assembled from proteins and nucleic acids. For example, filamentous phage (such as M13 phage) is a nanofiber (about 1 nm long and 7 nm wide) with multiple genetically modifiable proteins constituting a capsid and a DNA as a core inside the capsid. Since the DNA inside the phages encodes the proteins on the capsid, phages can be genetically engineered to bear the capability of targeting proteins, cells, tissues, and organs. Therefore, they are ideal for many applications in precision nanomedicine and regenerative medicine. This talk will summarize my group’s recent studies on the use of phages in these areas, including ultrasensitive biomarker detection for disease diagnosis, targeted drug delivery, directed stem cell differentiation, accelerated tissue formation, and nano-therapeutics for targeted disease treatment.
Bio
Chuanbin Mao is currently a Global STEM Professor at the Department of Biomedical Engineering of the Chinese University of Hong Kong and the director of Jockey Club STEM Lab of Nature-Inspired Precision Medical Engineering. He has been elected as a fellow of prestigious professional societies, including the American Association for the Advancement of Science (AAAS), American Academy of Microbiology (AAM), American Chemical Society (ACS), ACS Division of Polymeric Materials Science & Engineering (PMSE), American Institute for Medical and Biological Engineering (AIMBE), Biomedical Engineering Society (BMES), International Academy of Medical & Biological Engineering (IAMBE), and Royal Society of Chemistry (RSC). He is a recipient of multiple awards, including the US National Science Foundation (NSF) CAREER Award. He has published over 300 peer-reviewed articles in highly ranked journals such as Chemical Reviews, Science, Nature Materials, Nature Nanotechnology, Nature Communications, Advanced Materials, and Angewandte Chemie. His current research is focused mainly on phage bioengineering, biomaterials, biosensors, nanobiotechnology, nanomedicine, and regenerative medicine. [06/2024: h-index-80, 21877 citations]

Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou, China.,
[7:10 Coordinated Universal Time (UTC) | 18 Oct 2024 (Friday)]

Introduction
Talk
The Rise of Flexible Iontronics for Medical Intelligence. Abstract: The rise of flexible iontronics has provided unconventional yet inspiring alternatives to existing medical challenges in recent years. The emerging technology has illustrated its potential to achieve high-sensitivity high-precision biomechanical and biofluidic measurements in intimate contact with human epidermal surfaces, onto which can be easily attached, such as skin, hearts, blood vessels, eyes, joints and muscles. Real-time monitoring and feedback of biomechanical variations of human vitals can provide invaluable diagnostic and prognostic information over the cardiovascular, respiratory, and neuromuscular systems. Therefore, it has become a transformative initiative to improve both the accuracy and efficacy of future patient-centered medicine. Before the power of the emerging flexible iontronics can be fully revealed for medical purposes, several key technological challenges need to be addressed, including high-quality acquisition of biomechanical signals, high reliability and stability of bio-interface, as well as undisturbed patient-friendly measurement schemes. In this talk, the flexible iontronic sensing (FITS) mechanism, as the next-generation tactile sensing modality, will be introduced to tackle the aforementioned challenges, which offers the highest mechanical-to-capacitive sensitivity among all the tactile sensors, at least three orders of magnitude greater than that of the conventional counterparts, in addition to its ultrahigh signal-to-noise ratio and anti-interference performance. Another unique feature of iontronic sensing is the ubiquitous presence of ionic carriers in almost all natural surfaces, including human skin, which can be potentially unified into the device structure, leading to an extremely simplified hybrid architecture with the bio-interface seamlessly integrated...(click for more)
Bio
Professor Pan Tingrui is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE) and the Royal Society of Chemistry (RSC). He is currently a Yangtze River Chair Professor of the University of Science and Technology of China and directs the Institute for Innovative Medical Devices (iMED). Before joining USTC, Professor Pan was a tenured Full Professor at UC Davis, where he initiated Global Research Experience in Advanced Technologies (GREAT) Program and directed Center for Nano and Micro-Manufacturing (CNM²). He is currently an Associate Editor of Annals of Biomedical Engineering (TBME) and Journal of Medical Devices (JMD) and serves on the editorial board of Bioengineering and Journal of Chinese Medicine. His research interests span a wide range of bioengineering frontiers, including iontronic sensing, tactile intelligence, medical wearables, microfluidic interfaces and laboratory intelligence. His group has authored over 100 referenced publications on high impact journals and has been granted more than 20 international patents. Notably, Professor Pan is well known for his invention of the world-first flexible iontronic sensor (FITS), as the latest generation of tactile sensing technology, and has successfully translated it from a laboratory prototype to a series of industrial and medical products. For his contribution to both academic innovation and technology translation, Professor Pan has received a number of international awards and domestic recognitions, including the National Science Foundation (NSF) Early Career Development (CAREER) Award and Emerging Frontiers in Research and Innovation (EFRI) Award, Xerox Award, CES Innovation Award, UC Davis Outstanding Service Award, Outstanding Early-Career Engineering Faculty Award, and the First Prize of China Innovation and Entrepreneurship Competition.

Keynote Speakers

Faculty of Natural Sciences, Leibniz Universität Hannover, Hannover, Germany.

Introduction
Talk
Presentation Title: Advanced Cell Culture Technologies for Mesenchymal Stem Cell-Based Therapies (Session 1: Regenerative and Tissue Engineering )

Stevens Group, Kavli Institute for Nanoscience Discovery, Oxford, UK,
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

Introduction
Talk
Presentation Title: Post-printing functionalisation of 3D printed hydrogels as a modular biomaterials platform (Session 1: Regenerative and Tissue Engineering )

Department of Systems Engineering, École de Technologie Supérieure, Montreal, Quebec.

Introduction
Talk
Presentation Title: Kinematic assessment of the knee joint (Session 2: Biomechanics and Sports Medicine). Abstract: In this presentation, we will present the research that has been published in the last ten years on the use of an innovative piece of technology—the knee kinesiography exam. This exam relies on a harness (the KneeKG) attached on the shank and the thigh, which reduces soft tissue artifacts compared to methods using markers glued on the skin. On the harness are fixed optoeletronic markers, whose movements are followed by a portable optoelectronic camera (NDI). The exam consists of a calibration phase, followed by two 45 second walking periods on a treadmill. The system then automatically identifies biomechanical markers on the flexion/extension, ab/adduction and internal/external rotation curves. These markers, known to be related to pain and disease progression, are then translated into patient-specific exercises to be performed at home. Several medium and large cohort studies used the knee kinesiography exam to characterize three-dimensional knee kinematics in a healthy population, in various degrees of knee osteoarthritis, in patients who underwent unicompartmental or total knee arthroplasty and in patients who experienced a ligament rupture. This presentation will summarize the main results issued from these studies, highlighting the clinical usefulness of the technology for managing knee problems.

Faculty of Medicine and Health, University of Sydney, Sydney, Australia.

Introduction
Talk
Presentation Title: Assessing Bowling Legality in Cricket: Biomechanical Insights and Implications (Session 2: Biomechanics and Sports Medicine). Abstract: Cricket bowling has traditionally required a rigid arm, with no elbow straightening allowed. However, research shows that maintaining a completely rigid arm is impractical, which has led to rule changes. The current regulations mandate that the elbow's extension angle must not increase by more than 15 degrees. This study aims to determine whether this rule is upheld across various bowlers and styles and to explore if alternative kinematic measures can better distinguish between legal and suspect actions.

Biomaterials Engineering and Nanomedicine Biomaterials, Drug Delivery and Nanotechnology Unit Head, Center for Biomedical and Biomaterials Research (CBBR), University of Mauritius, Réduit, Mauritius

Introduction
Talk
Presentation Title: Biomaterials addressing health and climate change challenges (Session 3: Biomedical Biomaterials)

Department of Biomedical Engineering, The University of Memphis, Memphis, USA

Introduction
Talk
Presentation Title: Near-field Electrospinning Use in Fabricating the Next-generation Vascular Grafts (Session 3: Biomedical Biomaterials)

Deparment of Chemical Engineering, University of Leuven, Leuven, Belgium.

Introduction
Talk
Presentation Title: Biopolymers and bio hybrids for health and care (Session 4: Nano-Biotechnology)

Founding Editor-in-Chief, Bioengineering,
Founding Dean of Engineering, Anderson University SC,
President and Sr. Fellow, AIIMSEI

Introduction
Talk
Presentation Title: Modeling a Multi-modal Biochip for Physiological Status Monitoring in the Triage of Hemorrhagic Trauma and for Allograft Stratification (Session 4: Nano-Biotechnology)
Bio
Prof. Dr. Anthony Guiseppi-Elie is an international medical sciences, engineering, and innovation consultant at the American International Institute of Medical Sciences, Engineering, and Innovation. A former Vice President and Chief Academic Officer at Tri-County Technical College. He has 15 years of industrial research and product development experience and 18 years of experience as a tenured, titled, and endowed full professor at universities that include Virginia Commonwealth University, Clemson University, Texas A&M University, and Anderson University, where he was the Founding Dean of the College of Engineering. He has been associated with three startup companies and is Founder, President, and Scientific Director of ABTECH Scientific, Inc. A US citizen who was born in Trinidad and Tobago, he holds the Sc.D. in Materials Science and Engineering from MIT, the M.Sc. in Chemical Engineering from the University of Manchester (UMIST), and the B.Sc. (First Class Honors) in Applied, Analytical, and Biochemistry from the University of the West Indies (UWI). He has published over 225 peer-reviewed journal articles, holds 8 patents, and is a fellow of IEEE, AIMBE, BMES and the RSC. His research interests are in physiological monitoring during hemorrhagic trauma and allotransplantation, polymeric nanobiomaterials in drug delivery and tissue regeneration, and microanalytical systems in the service of human health and medicine.

School of Engineering, Ulster University, Belfast, UK

Introduction
Talk
Detection of Cardiovascular Disorders in Patients Supported with Continuous-Flow Left Ventricular Assist Devices by Monitoring Electrical Current Signals (Session 5: Biosignal Processing). Abstract: Continuous-flow left ventricular assist devices (CF-LVADs) are miniaturised devices implanted in end-stage heart failure patients to support the failing left ventricle. CF-LVADs alter the blood flow in the cardiovascular system, causing further complications. Additional health disorders during CF-LVAD support may increase morbidity and mortality in patients. Therefore, continuously monitoring blood flow through CF-LVADs may help to detect the complications early, allowing for timely interventions and reducing mortality in patients implanted with CF-LVADs. The lack of long-term reliable and implantable sensors in CF-LVADs does not allow for the real-time continuous monitoring of haemodynamic signals in the cardiovascular system. In this study, intrinsic CF-LVAD electrical current signals were continuously monitored and analysed to evaluate cardiac function and detect cardiovascular disorders. CF-LVAD electrical current signal waveforms over a 600 s period in patient-specific RR intervals were analysed to detect normal sinus rhythm, Atrial Fibrillation (AF) with unimodal and bimodal RR interval distributions, and right ventricular failure during CF-LVAD support...(click for more)

Department of Information Technology and Electrical Engineering, University of Napoli Federico II, Naples, Italy.

Introduction
Talk
Biosignal-based human-machine interfaces: a metrological approach to performance characterization (Session 5: Biosignal Processing). Abstract: One of the cornerstones of the current fifth industrial revolution (also known as Industry 5.0) is its emphasis on human-centricity, which necessitates the development of technologies increasingly tailored to human needs. A pivotal role in this context is played by Human-Machine Interfaces (HMIs), which enable seamless interaction between people and external devices. Beyond conventional tangible interfaces, such as controllers, keyboards, and mice, human-centricity is increasingly integrated into natural interfaces that leverage innate human actions, such as gaze, gestures, or voice and biosignals. In this groundbreaking context, a technically sound performance characterization becomes essential to ensure rapid and reliable transmission of information, particularly important when HMIs are used in critical contexts (such as the medical one). In this talk, a metrology-based approach for assessing the performance of natural HMIs will be presented with particular focus on HMIs based on biosignals. As a case study, two types of natural HMIs will be examined, specifically eye-tracking systems and visually evoked brain signals. These case studies will allow us to evaluate whether a given interface meets the requirements of its intended application, which can be particularly challenging in diverse scenarios ranging from industrial settings to healthcare.
Bio
Leopoldo Angrisani is Full Professor of Electrical and Electronic Measurements with the Department of Information Technology and Electrical Engineering of the University of Naples Federico II, Italy. He is also Chair of the Board of the Ph.D. Program ICTH - Information and Communication Technology for Health of the University of Naples Federico II. His research focuses on the role of measurement in the IoT field and, more generally, in the Industry 4.0 and Health 4.0 fields, cyber-physical measurement systems, measurement of ICT systems sustainability and sustainability of measurements, sensors, sensor networks, and measurement methods in precision agriculture and livestock farming, operation and performance assessment of communication systems, equipment, and networks, measurement uncertainty, impact of quantum technologies on measurements. He is currently the Coordinator of the Technical/Scientific Committee of MedITech – one of the eight Italian Competence Centers on I4.0 enabling technologies. He is Fellow of IEEE. He has chaired the IEEE Instrumentation & Measurement Society Italy Chapter since 2015. This chapter has received many awards, including the prestigious "Chapter of the Year 2021"award by the IEEE Region 8 (Europe, Middle Est, Africa). In 2021, he was awarded the “2021 IEEE Instrumentation and Measurement Society Technical Award” “For contributions in the advancement of innovative methods and techniques for communication systems test and measurement”. (H-index = 36; citations = 5208).

School of Biomedical Engineering, UPC-Peruvian University of Applied Science, Lima, Peru.

Introduction
Talk
Presentation Title: Functional Materials to Obtain Smart Microrobotics for Diagnostic and Therapy (Session 6: Biochemical Engineering). Abstract: Medical microrobots exhibit promise in acting as carriers for cancer cell therapy, effectively delivering drugs, and as manipulators equipped for biosensing, offering mobility and adaptability. These small robots are built using a combination of functional nano and micro-materials. The key to obtaining robots with multiple abilities lies in the precise combination of these materials. However, these materials have to be biocompatible with living systems. Herein, I will provide a comprehensive overview of different microrobots used for several biomedical applications. Focusing on the material composition for propelling, drug carrier, and mobile platform for sensing systems. In addition, their unique physical and chemical, mechanical, and optical, properties have been used to integrate into microrobots capable of achieving greater programmability to reach difficult access spaces and work in collective behaviors to ensure the desired task. Finally, the intricate challenge of creating a microrobot that integrates various physical and chemical functionalities will be demonstrated. These promise medical microrobots act as carriers for cancer cell therapy, effectively delivering drugs to eradicate bacterial biofilms and as manipulators equipped for biosensing. This innovative concept, revolutionizing the landscape of programmed robotics with multifaceted chemical and physical intelligence just using functional micro and nanomaterials.
Bio
Dr. Carmen Mayorga, currently is a professor at the School of Biomedical Engineering, UPC-Peruvian University of Applied Sciences previously she was a senior scientist at the Technical University of Ostrava and led the Kralupy unit from the Centre for Advanced Functional Nanorobots, UCT-Prague. She was a research fellow in the nanobioelectronics and biosensors group/ICN2, Barcelona-Spain, and at Nanyang Technological University, Singapore. Currently, her main research fields include the development of bio/sensors based on 2D-materials platforms functionalized with bioreceptors (enzyme, DNA, and antibodies) as well as micro/nano robotics at different scales and different propulsion modes for biomedical applications and environmental monitoring. Moreover, she is also interested in 2D-materials catalysis for energy applications.

Department of Physical and Analytical Chemistry, University of Oviedo, Spain.

Introduction
Talk
Development of bioelectrochemical platforms for decentralized and low-cost analysis of molecules of interest in clinical, food or environmental fields.

Invited Speakers

Prof. Dr. Gulden Camci-Unal

Department of Chemical Engineering Emerging Technologies & Innovation Center (ETIC), University of Massachusetts Lowell, Lowell, USA.

Introduction
Introduction
Talk: Unconventional Biomaterials for Tissue Engineering and Regenerative Medicine. Abstract: Regeneration of tissues damaged due to disease, trauma, degeneration, and aging represents a major medical need. Although surgical replacement can be performed to address this issue, insufficient number of donors limits the applicability of the approach. There is an unmet demand for development of tissue replacements. My work at the interface of biomaterials and biomedical engineering has made important contributions in generation of engineered biomaterial platforms through my multidisciplinary research background. To achieve my research goals, I use diverse tools from chemistry, cell biology, materials science, engineering, and medicine. In this seminar, I will talk about the functional biomaterials that we developed using unconventional approaches to generate tissue-mimetics for clinical applications. We developed multicellular and compartmentalized scaffolds for regenerative engineering, hydrogel-based platforms for personalized medicine, bioactive scaffolds for template-guided biomineralization, oxygen-generating biomaterials for tissue repair, micro/nanoparticle-reinforced hydrogels and origami-inspired approaches for bone tissue engineering, and hydrogel-based stem cell delivery approaches. I will also talk about my lab’s expertise on developing point of care (POC) diagnostic platforms for detection of pathogenic diseases (viral and bacterial), health conditions, forensic applications, and testing for environmental reagents. To overcome the limitations with the conventional methods, we develop rapid, portable, and reliable platforms for POC diagnostics. My lab’s research projects cover a broad range of applications including understanding fundamental biology to developing disease models for personalized medicine, tissue repair and regeneration, and rapid POC diagnostics. The overarching goal of my research is to improve human health and quality of life.

Prof. Dr. Franz Konstantin Fuss

1. Chair of Biomechanics, Faculty of Engineering Science, University of Bayreuth, Bayreuth, Germany 2. Division of Biomechanics, Department of Biomechatronic Systems, Fraunhofer Institute of Manufacturing Engineering and Automation IPA, Stuttgart, Germany

Introduction
Introduction
Talk: Dynamic balance diagnostics with smart insoles

Dr. Daria Podstawczyk

Department of Process Engineering and Technology of Polymer and Carbon Materials, Faculty of Chemistry, Wroclaw University of Science and Technology, Wrocław, Poland.

Introduction
Introduction
Talk: Coaxial 4D Printing of Thermoresponsive Hydrogel Soft Bioactuators with Embedded Perfusable Channels. Abstract: Most soft actuators have bimorph and planar structures, which allow them to deform only in the linear direction, e.g., bending. Recently, more attention has been paid to advanced, three-dimensional actuators with patterned structures and complex motions (1). A promising method for more precisely controlling material architecture involves the use of 4D printing technology. 4D printing is an emerging fabrication technology that offers precise manufacturing with great potential in various engineering applications, including soft biorobots. It enables the creation of dynamic and responsive structures using 3D printing techniques and materials capable of changing shape over time (the fourth dimension). Here, we focus on the swelling/deswelling phenomena in thermoresponsive hydrogels as the driving force for changing material shape in response to stimuli. We developed a protocol for producing new advanced functional PNIPAAm-based biomaterial inks for coaxial 4D printing of biomaterials. These biomaterials have a geometrically designed internal microstructure and architecture, capable of reversibly expanding and contracting in response to temperature changes (2). This was achieved by designing oriented microstructures and patterned macrostructures with perfusable channels embedded within the 4D-printed hydrogel (3). We also investigated the physics of anisotropy of the printed hydrogel and conducted physicochemical, rheological, and mechanical characterization of the functional inks and 4D-printed objects. This confirmed the interrelation between material properties and shape morphing behavior.

Dr. Andrew Robbins

Department of Mechanical Engineering, University of Texas at Tyler, Tyler, USA.

Introduction
Introduction
Talk: Learning how Sheep Move: Developing a General Inverse Kinetic Model for Sheep. Abstract: Introduction: Whole body inverse kinetic models of humans are well developed. However, for animal models of human disease, the prevalent tools in human biomechanics do not exist. This work explores the development of whole body biomechanical models of quadrupeds, and presents preliminary results in the development of a whole body biomechanical model for sheep in OpenSIM, for use with motion capture data. We present statistical and machine learning models for predicting the hip joint centers from anatomical measurements and landmarks, as well as models for predicting the mass and inertial properties of sheep body segments. Methods: CT scans from 16 sheep of varying ages, weight, sex, and phenotypes were acquired and the data used to calculate the known hip joint center by sphere fitting the femoral head. Anatomical measurements and additional subject information were used to create models to estimate the hip joint centers in absence of CT data. Then, the mass and moments of inertia for each body segment were estimated from the CT scans, and predictive models applied in the absence of CT scans. Results: Hip joint centers were predicted with much greater accuracy than previous methods, with errors on the order of a few millimeters, depending on the animal. Mass and inertial properties were predicted with less accuracy, with errors typically within 10%, but in some cases exceeding 20%. Conclusions: This work represents a significant new set of data for biomechanical models of sheep, being the first comprehensive study to include data from multiple animals. However, our data set is still limited, and would significantly benefit from a larger set of animals to be included. Additionally, sensitivity analysis on the models produced using this data will need to be performed to determine the extent to which errors in the various parameters affect final kinetic analyses.

Prof. Dr. Michael Moreno

Department of Mechanical Engineering, J. Mike Walker ’66 Faculty, Texas A&M University, Texas, USA.

Introduction
Introduction
Talk: Learning how Sheep Move: Developing a General Inverse Kinetic Model for Sheep. Abstract: Introduction: Whole body inverse kinetic models of humans are well developed. However, for animal models of human disease, the prevalent tools in human biomechanics do not exist. This work explores the development of whole body biomechanical models of quadrupeds, and presents preliminary results in the development of a whole body biomechanical model for sheep in OpenSIM, for use with motion capture data. We present statistical and machine learning models for predicting the hip joint centers from anatomical measurements and landmarks, as well as models for predicting the mass and inertial properties of sheep body segments. Methods: CT scans from 16 sheep of varying ages, weight, sex, and phenotypes were acquired and the data used to calculate the known hip joint center by sphere fitting the femoral head. Anatomical measurements and additional subject information were used to create models to estimate the hip joint centers in absence of CT data. Then, the mass and moments of inertia for each body segment were estimated from the CT scans, and predictive models applied in the absence of CT scans. Results: Hip joint centers were predicted with much greater accuracy than previous methods, with errors on the order of a few millimeters, depending on the animal. Mass and inertial properties were predicted with less accuracy, with errors typically within 10%, but in some cases exceeding 20%. Conclusions: This work represents a significant new set of data for biomechanical models of sheep, being the first comprehensive study to include data from multiple animals. However, our data set is still limited, and would significantly benefit from a larger set of animals to be included. Additionally, sensitivity analysis on the models produced using this data will need to be performed to determine the extent to which errors in the various parameters affect final kinetic analyses.

Prof. Dr. Seda Kizilel

College of Chemical & Biological Engineering, Koç University, Istanbul, Turkey.

Introduction
Introduction
Talk: Designing immunologically invisible spheroids using biomaterials, genetic engineering and machine learning. Abstract: One of the main obstacles in cell transplantation is the need for immunosuppressive drugs to prevent rejection. These medications carry risks, including increased susceptibility to infections and systemic immunosuppression. In addition, the availability of donor islet cells is limited, making it difficult to scale up this treatment option. To address these challenges, we are exploring innovative strategies to enhance the function of implanted cells such as insulin secreting islets. One approach involves the development of biomaterials that can shield transplanted islets from immune attack while still allowing for the exchange of essential nutrients and signaling molecules. The other one that we use involves machine learning, where we use artifical neural network modeling algorithms to predict the permeability and crosslink density of the biomaterials that we use to shield transplanted cells. The last strategy is the use of genetic engineering where the genome of the cells can be edited to render them "invisible" to the immune system, reducing the risk of rejection and improving long-term outcomes. We aim to create a protective barrier around transplanted islet cells while simultaneously enhancing their immune tolerance thorugh genetic manipulations. Our approach holds promise for improving the efficacy and durability of islet transplantation as a treatment for many diseases that involve cell transplantation, including type 1 diabetes.

Dr. Hana Lísalová

Department of Optical and Biophysical Systems, Division of Optics, FZU - Institute of Physics of the Czech Academy of Sciences, Prague, Czechia.

Introduction
Introduction
Talk: Advancing Cell-on-a-Chip Interfaces with Bio-functional Terpolymer Nano-Brushes Exhibiting Strong Resistance to Bacterial Adhesion. Abstract: Bioengineering plays a crucial role in developing advanced biomedical devices and interfaces that integrate biological systems. One major challenge in the development of cell-on-a-chip interfaces is preventing bacterial contamination while maintaining cellular compatibility. Low-fouling, (super-)hydrophilic zwitterionic polymer materials have emerged as potential biomedical materials and bio-functional coatings. Here, we report a novel terpolymer nano-brush coating that effectively suppresses undesired biomolecular fouling and biofilm formation while providing a sufficient molecular functionalization capacity.

Dr. Eduardo Espinoza

Department of Inorganic Chemistry and Chemical Engineering, University of Cordoba, Cordoba, Spain.

Introduction
Introduction
Talk: Biopolymers and 3D Bioprinting

Ms. Daniela Pedrozo Roca

INBIO, Faculty of Engineering, National University of San Juan, San Juan, Argentina.

Introduction
Introduction
Talk: Functional Characterization of Brain Areas Using Functional Magnetic Resonance Imaging. Abstract: Functional magnetic resonance imaging (fMRI) is a non-invasive neuroimaging modality that is continuously growing, both in the clinical and scientific fields. The analysis of these images requires a very complex and varied post-processing of the obtained images. This causes the results of different studies to be non-comparable or difficult to characterize. In order to simplify the processing and obtain objective results with analyzable metrics, this work proposes the development of an analysis methodology to obtain statistical values on brain activation areas segmented by region.

Prof. Dr. Silviya Petrova Zustiak

Department of Biomedical Engineering, SLU Institute for Drug and Biotherapeutic Innovation, Saint Louis University, St. Louis, USA.

Introduction
Introduction
Talk: Development of Super-Lubricious Hydrogel Microspheres for the Treatment of Knee Osteoarthritis. Abstract: Osteoarthritis (OA) significantly alters the microenvironment of the knee, increasing inflammation and reducing lubricity. Consequently, OA can result in debilitating pain that necessitates a total joint replacement. Here, we developed super-lubricious hydrogel microspheres to reduce friction and inflammation within the synovium. Hydrogel microspheres were fabricated using polyethylene glycol and subsequently coated with a custom-synthesized copolymer. This copolymer consisted of monomers of dopamine methacrylate (DMA), which provides the microspheres with strong attachment properties, and sulfobetaine methacrylate (SBMA), which provides lubrication due to its zwitterionic nature. The optimization of DMA:SBMA ratios, as well as the copolymers' arrangement (block vs. random copolymer), is currently underway to balance microsphere adhesion and lubricity. Microsphere lubricity was tested using a custom-built tribo-rheometer that enables the quantification of friction coefficients for small sample volumes (140 µL compared to 500 µL for standard tribology set-ups). Copolymer-coated microspheres demonstrated lower friction compared to uncoated microspheres, as well as the synovial fluid derived from patients with varying degrees of osteoarthritis or knee ligament tears. Additionally, the coated microspheres were shown to be injectable, allowing for facile in situ delivery. When injected intra-articularly into the knee capsule of healthy mice, the microspheres persisted for over 10 days and did not cause pain or interfere with daily mice activities. Our current work is focused on loading the microspheres with disease-modifying therapeutic molecules, such as platelet-rich plasma (PRP), and testing those in mice models of OA.

Registration


The registration for IOCBE 2024 will be free of charge! The registration includes attendance to all conference sessions.

If you are registering several people under the same registration, please do not use the same email address for each person, but their individual university email addresses. Thank you for your understanding.

Please note that the submission and registration are two separate parts. Only scholars who registered can receive a link to access the conference live streaming. The deadline for registration is 10th October 2024.

Instructions for Authors

Procedure for Submission

The 1st International Online Conference on Bioengineering will accept abstracts only. The accepted abstracts will be available online on Sciforum.net during and after the conference.

Important Deadlines

1. Extended deadline for abstract submission: 1̶7̶ ̶J̶u̶n̶e̶ ̶2̶0̶2̶4̶ 17 July 2024
2. Extended deadline for abstract acceptance notification:1̶7̶ ̶J̶u̶l̶y̶ ̶2̶0̶2̶4̶ 17 August 2024. You will be notified of the acceptance of an oral/poster presentation in a separate email.

Abstract Submission

Abstract submissions should be completed online by registering with www.sciforum.net and Submit Abstract. No physical template is necessary.

1. Your abstract should be include an introduction, methods, results and discussion, and conclusions sections. Abstracts should be 200–300 words in length. Please prepare your abstract in Microsoft Word or another word processing software and then cut and paste the text into the submission portal (see below for more details).
2. Abstract submissions should be completed online by registering [Register] with www.sciforum.net . If you are already registered then please Login to Submit Abstract.
3. All accepted abstracts will be published as part of a single dedicated volume of Engineering Proceedings (indexed within Scopus, ISSN: 2673-4591) after quality check. If you wish to publish a full-length proceedings paper, please refer to the “Publication Opportunities” Section.
4. All abstracts should be submitted and presented in clear, publication-ready English with accurate grammar and spelling.
5. You may submit multiple abstracts. However, only one abstract will be selected for the oral presentation.
6. The abstracts submitted to this conference must be original and novel, without prior publication in any journals or it will not be accepted to this conference.

Detailed Requirements:
1. The submitting author must ensure that all co-authors are aware of the contents of the abstract.
2. Please select only one presenter for each submission. If you would like to change the presenter after submission, please email us accordingly.

3. The presenting author must fill in "Biography" when adding submission authors.
Note: We only accept live presentations.

Template:

(Cut and paste the contents of your abstract into the online portal at Submit Abstract.)
Abstract Title:
(Total word count: 200-300 words maximum)
Introduction:
Methods:
Results and Discussion:
Conclusions:
Authors and Affiliations:
Oral Presentation and Slides Submission
The slot for the oral presentation is 15 mins. We advise that your presentation lasts for a maximum of 12 mins, leaving at least 3 mins for the Q&A session.
Authors are encouraged to prepare a presentation in PowerPoint or similar software.
Poster Presentation
All accepted posters will be permanently exhibited online in the Poster Gallery.

Poster:
  • Should include the title, authors, contact details and main research findings, as well as tables, figures and graphs where necessary.
  • File format: PDF (.pdf).
  • Size in pixel: 1,080 width x 1,536 height–portrait orientation.
  • Size in cm: 38.1 width x 54.2 height–portrait orientation.
  • Font size: ≥16.
Examples of successful submissions can be viewed here at the following links: (1), (2), (3)
You can use our free template to create your poster. The poster template can be downloaded here.

We will reach out to you closer to the dates of the conference with more information.
Potential Conflicts of Interest

It is the authors' responsibility to identify and declare any personal circumstances or interests that may be perceived as inappropriately influencing the representation or interpretation of clinical research. If there is no conflict, please state "The authors declare no conflicts of interest." This should be conveyed in a separate "Conflict of Interest" statement preceding the "Acknowledgments" and "References" sections at the end of the manuscript. Any financial support for the study must be fully disclosed in the "Acknowledgments" section.

Copyright

MDPI, the publisher of the Sciforum.net platform, is an open access publisher. We believe authors should retain the copyright to their scholarly works. Hence, by submitting an abstract to this conference, you retain the copyright to the work, but you grant MDPI the non-exclusive right to publish this abstract online on the Sciforum.net platform. This means you can easily submit your full paper (with the abstract) to any scientific journal at a later stage and transfer the copyright to its publisher if required.

Publication Opportunity

1. Bioengineering Journal Publication
Participants in this conference are cordially invited to contribute a full manuscript to the conference's Special Issue, published in Bioengineering (ISSN 2306-5354, Impact Factor 3.8), with a 20% discount on the publication fee. Details of the special issue will be announced here later. Please note if you have IOAP/association discounts, conference discounts will be combined with IOAP/association discounts. Conference discounts cannot be combined with reviewer vouchers. All submitted papers will undergo MDPI’s standard peer-review procedure. The abstracts should be cited and noted on the first page of the paper.

2. Proceeding Paper Publication
You are welcome to submit a proceeding paper (3-6 pages) to Engineering Proceedings (indexed within Scopus, ISSN: 2673-4591) after the conference. Publication of the proceedings will be free of charge.
Authors are asked to disclose that it is a proceeding paper of the IOCBE2024 conference paper in their cover letter.
Proceedings submission deadline: 2 December 2024
Carefully read the rules outlined in the 'Instructions for Authors' on the journal’s website and ensure that your submission adheres to these guidelines.

Manuscripts for the proceedings issue must be formatted as follows:
  • Title.
  • Full author names.
  • Affiliations (including full postal address) and authors' e-mail addresses.
  • Abstract.
  • Keywords.
  • Introduction.
  • Methods.
  • Results and Discussion.
  • Conclusions.
  • Acknowledgements.
  • References.

IOCBE 2024-proceeding template

Event Awards

To acknowledge the support of the conference's esteemed authors and recognize their outstanding scientific accomplishments, we are pleased to announce that the conference will provide multiple awards including MDPI Bioengineering Lectureship 2024 Award, Best Oral Presentation Awards and Best Poster Awards.

The Awards
MDPI Bioengineering Lectureship 2024

Number of Awards Available: 1

Nominate your candidate today.

Lecture delivered at the 1st International Online Conference on Bioengineering (IOCBE) on 16-18 October 2024.
Bioengineering in the World of Generative AI

The MDPI Bioengineering Lectureship award:

1. The successful nominee will deliver the MDPI Bioengineering Lecture at the 1st International Online Conference on Bioengineering (IOCBE) on 16-18 October 2024.
2. They will also receive a two year's article processing charge (APC) discounts for any future publications in Bioengineering.
3. They will be granted a travel award of CHF 1,000 CHF with which to attend the World Congress in Bioengineering.

Best Oral Presentation Awards and Best Poster Awards

Number of Awards Available: 3

The Best Oral Presentation Awards are given to the paper judged to make the most significant oral contribution to the conference.
The Best Poster Awards are given to the submission judged to make the most significant and interesting poster for the conference.

There will be three winners selected for these awards.
The winner will receive a certificate, 200 CHF and 1 Bioengineering APC credit of 2,700CHF each.
Terms and Conditions:
Eligible nominees (for MDPI Bioengineering Lectureship 2024):
Eligible lectureship candidates meet the following criteria:
1.Must be an early-career independent researcher who earned their degree within the last 10 years (doctoral students and postdoctoral scholars in a PI’s lab are not eligible).
2.Must be actively engaged in research in the bioengineering field and have made a noteworthy contribution to the field.

How to nominate:
Nominations can be made via email to iocbe@mdpi.com and must include the following:
1. The name, affiliation and contact details of the nominee, nominator, and referee.
2. An up-to-date biography of a maximum of 300 words and an up-to-date CV of the nominee, which should be no longer than 2 pages.
3. A letter of recommendation (500 words or less) from the nominator. The relationship between nominator and nominee should be clearly stated in this letter.
4. A supporting letter of recommendation (500 words or less) from a referee who is familiar with the nominees’ temperament and promise as a scholar, e.g., the nominee’s academic mentor or PhD/postdoc supervisor. The relationship between the referee and nominee should be clearly stated in this letter.
5. The nominator must confirm that, to the best of their knowledge, their nominee is in good professional standing and that there is no confirmed or potential impediment to them receiving the Lectureship.

The MDPI Bioengineering Lectureship award:
1. The successful nominee will deliver the MDPI Bioengineering Lecture at the 1st International Online Conference on Bioengineering (IOCBE) on 16-18 October 2024.
2. They will also receive a two year's article processing charge (APC) discounts for any future publications in Bioengineering.
3. They will be granted a travel award of CHF 1,000 CHF with which to attend the World Congress in Bioengineering.

Sponsors and Partners

For information regarding sponsorship and exhibition opportunities, please click here.

Organizers


Media Partners

Conference Secretariat

Mr. Lionel Zheng
Mr. Spatar Ionut
Email: iocbe@mdpi.com

For inquiries regarding submissions and sponsorship opportunities, please feel free to contact us.
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