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Joo Beom Eom   Dr.  Senior Scientist or Principal Investigator 
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Joo Beom Eom published an article in September 2018.
Top co-authors See all
Seok-Ki Kim

76 shared publications

Department of Nuclear Medicine

Soyoun Jung

54 shared publications

Samsung Display. Co. Ltd.; Youngin 446-711 Korea

Taeksoo Ji

22 shared publications

Chonnam National University, Gwangju, Korea (The Republic of)

Byeong-Il Lee

16 shared publications

Korea Photonics Technology Institute

In Hee Shin

6 shared publications

Korea Photonics Technology Institute, Korea (the Republic of)

28
Publications
34
Reads
1
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133
Citations
Publication Record
Distribution of Articles published per year 
(2002 - 2018)
Total number of journals
published in
 
17
 
Publications See all
Article 0 Reads 2 Citations Responsive alginate-cisplatin nanogels for selective imaging and combined chemo/radio therapy of proliferating macrophag... Suk Ho Hong, Yan Li, Joo Beom Eom, Yongdoo Choi Published: 01 September 2018
Quantitative Imaging in Medicine and Surgery, doi: 10.21037/qims.2018.09.01
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Atherosclerosis is a major global health concern. Targeting macrophages is hypothesized as an alternative treatment for atherosclerosis. We synthesized alginate-based cisplatin-loaded nanogels (TANgel) as a pH-responsive drug-releasing theranostic nanoplatform for macrophage cells. Carboxylic acid groups of alginic acid were modified with iminodiacetic acid (IDA) to enhance chelation of platinum ions. The near infrared (NIR) fluorophore ATTO655 was conjugated to the modified alginic acid. Cisplatin was used as an antiproliferation drug and as a crosslinking agent between alginate molecules to form TANgel. Release behavior of cisplatin from TANgel was analyzed under different pH conditions. Cellular uptake and therapeutic efficacy of TANgel were tested in the macrophage cell line J774A.1 and normal human cell lines such as HDMVECn. The nanogel had a narrow size distribution of approximately 100 nm. The nanogel showed highly pH-responsive drug release behavior. All incorporated cisplatin was released at pH 5 within 48 h, while less than 15% was released at pH 7.4. The nanogel was preferentially taken up by J774A.1 cells compared to normal human cells, enabling selective NIR fluorescence imaging and chemotherapy of macrophage cells. In addition, the nanogel formulation lowered the therapeutic concentration of the drug with and without low dose radiation therapy (RT) compared to the free drug form. This nanogel system may have potential utility for selective NIR fluorescence imaging and combined chemo/radio therapy of proliferating macrophage cells in atherosclerotic regions, allowing for reduction of systemic toxicity.
Article 5 Reads 0 Citations Determination of organic compounds in water using ultraviolet LED Chihoon Kim, Taeksoo Ji, Joo Beom Eom Published: 14 March 2018
Measurement Science and Technology, doi: 10.1088/1361-6501/aaa364
DOI See at publisher website ABS Show/hide abstract
In this paper, we demonstrate the detection of organic compounds in water by applying an ultraviolet LED (280 nm) spectroscopy system and photodetector. The LED spectroscopy system showed a high correlation between the prepared potassium hydrogen phthalate (KHP) concentration and that calculated by multiple linear regressions, indicating an adjusted coefficient of determination from 0.953 to 0.993. In addition, a comparison between the spectroscopy system and total organic carbon analyzer indicated that the concentration differences were small. Based on the close correlation between the spectroscopy and photodetector absorbance values, organic measurement with photodetector could be configured for monitoring.
PROCEEDINGS-ARTICLE 2 Reads 0 Citations A three-dimensional scanning apparatus based on structured illumination method and its application in dental scanning Jae Sung Ahn, Anjin Park, Ju Wan Kim, Byeong Ha Lee, Joo Beo... Published: 23 August 2017
Applied Optical Metrology II, doi: 10.1117/12.2271018
DOI See at publisher website
Article 4 Reads 3 Citations Development of Three-Dimensional Dental Scanning Apparatus Using Structured Illumination Jae Sung Ahn, Anjin Park, Ju Wan Kim, Byeong Ha Lee, Joo Beo... Published: 15 July 2017
Sensors, doi: 10.3390/s17071634
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
We demonstrated a three-dimensional (3D) dental scanning apparatus based on structured illumination. A liquid lens was used for tuning focus and a piezomotor stage was used for the shift of structured light. A simple algorithm, which detects intensity modulation, was used to perform optical sectioning with structured illumination. We reconstructed a 3D point cloud, which represents the 3D coordinates of the digitized surface of a dental gypsum cast by piling up sectioned images. We performed 3D registration of an individual 3D point cloud, which includes alignment and merging the 3D point clouds to exhibit a 3D model of the dental cast.
Article 2 Reads 0 Citations Terahertz transmission properties of silicon wafers using continuous-wave terahertz spectroscopy Chihoon Kim, Jae Sung Ahn, Taeksoo Ji, Joo Beom Eom Published: 06 February 2017
Measurement Science and Technology, doi: 10.1088/1361-6501/aa57e5
DOI See at publisher website
Article 3 Reads 3 Citations Continuous wave terahertz spectroscopy system with stably tunable beat source using optical switch Joo Beom Eom, Chihoon Kim, Jaesung Ahn Published: 01 January 2017
Optics Communications, doi: 10.1016/j.optcom.2016.08.067
DOI See at publisher website
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