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Anna Costa   Dr.  Institute, Department or Faculty Head 
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Anna Costa published an article in March 2018.
Top co-authors See all
Bernd Nowack

194 shared publications

Empa, Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland

Vicki Stone

164 shared publications

Heriot-Watt University, Riccarton Campus, Edinburgh, EH14 4AS, United Kingdom

Michele Dondi

143 shared publications

CNR-ISTEC, National Research Council-Institute of Science and Technology for Ceramics, Via Granarolo, 64-48018 Faenza (RA), Italy;(C.Z.);(M.D.)

Wendel Wohlleben

121 shared publications

Advanced Materials Research

Teresa Fernandes

101 shared publications

Heriot-Watt University, Riccarton Campus, Edinburgh, EH14 4AS, United Kingdom

Publication Record
Distribution of Articles published per year 
(2006 - 2018)
Total number of journals
published in
Publications See all
Article 0 Reads 1 Citation Coatings made of proteins adsorbed on TiO2 nanoparticles: a new flame retardant approach for cotton fabrics Simona Ortelli, Giulio Malucelli, Fabio Cuttica, Magda Blosi... Published: 15 March 2018
Cellulose, doi: 10.1007/s10570-018-1745-z
DOI See at publisher website
Article 4 Reads 1 Citation Hazard Screening Methods for Nanomaterials: A Comparative Study Barry Sheehan, Finbarr Murphy, Martin Mullins, Irini Furxhi,... Published: 25 February 2018
International Journal of Molecular Sciences, doi: 10.3390/ijms19030649
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Hazard identification is the key step in risk assessment and management of manufactured nanomaterials (NM). However, the rapid commercialisation of nano-enabled products continues to out-pace the development of a prudent risk management mechanism that is widely accepted by the scientific community and enforced by regulators. However, a growing body of academic literature is developing promising quantitative methods. Two approaches have gained significant currency. Bayesian networks (BN) are a probabilistic, machine learning approach while the weight of evidence (WoE) statistical framework is based on expert elicitation. This comparative study investigates the efficacy of quantitative WoE and Bayesian methodologies in ranking the potential hazard of metal and metal-oxide NMs—TiO2, Ag, and ZnO. This research finds that hazard ranking is consistent for both risk assessment approaches. The BN and WoE models both utilize physico-chemical, toxicological, and study type data to infer the hazard potential. The BN exhibits more stability when the models are perturbed with new data. The BN has the significant advantage of self-learning with new data; however, this assumes all input data is equally valid. This research finds that a combination of WoE that would rank input data along with the BN is the optimal hazard assessment framework.
Article 0 Reads 5 Citations Nanoencapsulation techniques as a “safer by (molecular) design” tool Simona Ortelli, Anna Luisa Costa Published: 01 February 2018
Nano-Structures & Nano-Objects, doi: 10.1016/j.nanoso.2016.03.006
DOI See at publisher website
Article 0 Reads 6 Citations Silver nanoparticles as a medical device in healthcare settings: a five-step approach for candidate screening of coating... Valentina Marassi, Luisana Di Cristo, Stephen G. J. Smith, S... Published: 31 January 2018
Royal Society Open Science, doi: 10.1098/rsos.171113
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Silver nanoparticle-based antimicrobials can promote a long lasting bactericidal effect without detrimental toxic side effects. However, there is not a clear and complete protocol to define and relate the properties of the particles (size, shape, surface charge, ionic content) with their specific activity. In this paper, we propose an effective multi-step approach for the identification of a ‘purpose-specific active applicability window’ to maximize the antimicrobial activity of medical devices containing silver nanoparticles (Ag NPs) (such as surface coaters), minimizing any consequent risk for human health (safety by design strategy). The antimicrobial activity and the cellular toxicity of four types of Ag NPs, differing in their coating composition and concentration have been quantified. Through the implementation of flow-field flow fractionation, Ag NPs have been characterized in terms of metal release, size and shape. The particles are fractionated in the process while being left unmodified, allowing for the identification of biological particle-specific contribution. Toxicity and inflammatory response in vitro have been assessed on human skin models, while antimicrobial activity has been monitored with both non-pathogenic and pathogenic Escherichia coli. The main benefit associated with such approach is the comprehensive assessment of the maximal effectiveness of candidate nanomaterials, while simultaneously indexing their properties against their safety.
Article 6 Reads 3 Citations Environmental Impacts by Fragments Released from Nanoenabled Products: A Multiassay, Multimaterial Exploration by the SU... Mónica J.B. Amorim, Sijie Lin, Karsten Schlich, José M. Nava... Published: 27 January 2018
Environmental Science & Technology, doi: 10.1021/acs.est.7b04122
DOI See at publisher website
Article 0 Reads 0 Citations Silica modification of titania nanoparticles enhances photocatalytic production of reactive oxygen species without incre... Simona Ortelli, Anna L. Costa, Pietro Matteucci, Mark R. Mil... Published: 01 January 2018
RSC Advances, doi: 10.1039/c8ra07374k
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Titania (TiO2) nanoparticles were surface modified using silica and citrate to implement a ‘safe-by-design’ approach for managing potential toxicity of titania nanoparticles by controlling surface redox reactivity.